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Intensive Care Medical and Health News Headlines
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All Recent Intensive Care Medical News Headlines |
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Severe myocardial depression in a patient with aluminium phosphide poisoning: A clinical, electrocardiographical and histopathological correlation
We report a case where the heart was the predominantly affected organ. We describe the clinical symptoms and signs and their correlation with electrocardiographic and histopathological examinations. (Source: Indian Journal of Critical Care Medicine)...
POSTED 07/01/2009 at 01:16 PM --

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Cerebritis: An unusual complication of <i> Klebsiella pneumoniae</i>
We report a case of <i> Klebsiella</i> cerebritis in an adult patient with a proven extracranial focus of infection. We suggest considering cerebritis as a differential diagnosis for altered level of consciousness in patients of severe sepsis, even if an extracranial source of infection is proven. (Source: Indian Journal of Critical Care Medicine)...
POSTED 07/01/2009 at 01:16 PM --

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Acute fatty liver of pregnancy: A case report of an uncommon disease
Vora Kalpana S, Shah Veena R, Parikh Geeta PIndian Journal of Critical Care Medicine 2009 13(1):34-36A 24-year-old female at 34-week gestation, presented with malaise, nausea, vomiting, jaundice, and absent foetal movements. A clinical diagnosis of acute fatty liver of pregnancy was made. Although early caesarean section was performed, postoperative course was complicated by acute respiratory distress syndrome (ARDS) sepsis, and continuing coagulopathy. Supportive management in an intensive care unit resulted in successful outcome. (Source: Indian Journal of Critical Care Medicine)...
POSTED 07/01/2009 at 01:16 PM --

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Organophosphate or organochlorines or something else....?
We present here such a case of deltamethrin poisoning. (Source: Indian Journal of Critical Care Medicine)...
POSTED 07/01/2009 at 01:16 PM --

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Challenges in critical care services in Sub-Saharan Africa: Perspectives from Nigeria
Okafor U VIndian Journal of Critical Care Medicine 2009 13(1):25-27Critical care services in Nigeria and other West African countries had been hampered by economic reversals resulting in low wages, manpower flight overseas, government apathy towards funding of hospitals, and endemic corruption. Since then things have somewhat improved with the government's willingness to invest more in healthcare, and clampdown on resource diversion in some countries like Nigeria. Due to the health needs of these countries, including funding and preventive medicine, it may take a long time to reach reasonably high standards. Things are better than they were several years ago and that gives cause for optimism, especially with the debt cancellation by Western nations for most countries in the region. ......
POSTED 07/01/2009 at 01:16 PM --

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Aluminum phosphide poisoning: Effect of correction of severe metabolic acidosis on patient outcome
Jaiswal S, Verma R K, Tewari NIndian Journal of Critical Care Medicine 2009 13(1):21-24Forty patients of aluminum phosphide poisoning who were admitted to the ICU of Sir Sunder Lal Hospital, Banaras Hindu University, were studied. Restlessness, excessive thirst, shock, arrhythmias, tachypnoea, and severe metabolic acidosis were the common clinical findings. Only repeated and full correction with intravenous sodium bicarbonate was able to cope up with the severity and rapidity of acidosis. There was no significant change in blood pressure, pulse rate, and respiratory rate after full correction but gradually pulse and systolic blood pressure settled after ionotropic support in the survivors. There was significant improvement from 30.36% in the case when only half correction was done, ......
POSTED 07/01/2009 at 01:16 PM --

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A comparative study to assess the effect of amikacin sulfate bladder wash on catheter-associated urinary tract infection in neurosurgical patients
Conclusions:</b> Amikacin sulfate bladder wash was effective in preventing CAUTI. It can thus decrease the antibiotic usage thereby preventing the emergence of antibiotic resistance. (Source: Indian Journal of Critical Care Medicine)...
POSTED 07/01/2009 at 01:16 PM --

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Changes of splanchnic perfusion after applying positive end expiratory pressure in patients with acute respiratory distress syndrome
Conclusion: </b> PEEP of 10-20 cmH<sub> 2</sub> O does not affect splanchnic perfusion and is hemodynamically well tolerated in most patients with ARDS, including those receiving inotropic supports. (Source: Indian Journal of Critical Care Medicine)...
POSTED 07/01/2009 at 01:16 PM --

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Alveolar recruitment maneuvers in acute lung injury/acute respiratory distress syndrome
Chacko Jose, Rani UshaIndian Journal of Critical Care Medicine 2009 13(1):1-6Mechanical ventilation can worsen lung damage in acute lung injury and acute respiratory distress syndrome. The use of low tidal volumes is one of the strategies that has been shown to reduce lung injury and improve outcomes in this situation. However, low tidal volumes may lead to alveolar derecruitment and worsening of hypoxia. Recruitment maneuvers along with positive end-expiratory pressure may help to prevent derecruitment. Although recruitment maneuvers have been shown to improve oxygenation, improved clinical outcomes have not been demonstrated. The optimal recruitment strategy and the type of patients who might benefit are also unclear. This review summarizes the impact of recruitment maneuvers on lung mec......
POSTED 07/01/2009 at 01:16 PM --

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Broadening our perspectives on ICU delirium risk factors
ICU delirium is associated with poor patient outcome. Risk factor stratification is essential to the understanding, prevention and treatment of this disorder. Alcohol consumption, smoking and prior cognitive impairment appear strongly correlated with delirium risk. Several potentially modifiable associations deserve prospective study: these include administration of sedatives and opiates; multiple catheters; as well as minimizing physical restraints and enabling visitors. (Source: Critical Care)...
POSTED 06/30/2009 at 06:00 PM --

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Serum Interleukin-6 and interleukin-8 are early biomarkers of acute kidney injury and predict prolonged mechanical ventilation in children undergoing cardiac surgery: a case-control study
Conclusions:
Serum IL-6 and IL-8 identifies AKI early in patients undergoing cardiopulmonary bypass surgery. Furthermore, amongst patients with AKI, high IL-6 levels are associated with prolonged mechanical ventilation, suggesting that circulating cytokines in patients with AKI may have deleterious effects on other organs, including the lungs. (Source: Critical Care)...
POSTED 06/30/2009 at 06:00 PM --

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The international PROGRESS registry of patients with severe sepsis: drotrecogin alfa (activated) use and patient outcomes
IntroductionSince the launch of drotrecogin alfa activated (DrotAA), institutions and individual countries have published data on its use in clinical practice, based on audit or registry data. These studies were limited in size and geographic locale and included patients with greater disease severity and higher mortality than those in clinical trials. The purpose of this study was to compare baseline characteristics and clinical outcomes (using appropriate statistical adjustments) of patients treated or not treated with DrotAA from the international PROGRESS (Promoting Global Research Excellence in Severe Sepsis) cohort study of severe sepsis.
Methods:
PROGRESS was a global, non-interventional, multi-center, prospective, observational study of patients having a diagnosis of severe sepsis t......
POSTED 06/29/2009 at 06:00 PM --

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Tight glycemic control and computerized decision-support systems: a systematic review
Conclusions While most studies evaluating the effect of CDSS on the quality of the TGC process found improvement when evaluated on the
basis of the quality indicators used, it is impossible to define the exact success factors, because of simultaneous implementation
of the CDSS with a new or modified TGC protocol and the hybrid solutions used to integrate the CDSS into the clinical workflow.
Content Type Journal ArticleCategory ReviewDOI 10.1007/s00134-009-1542-0Authors
Saeid Eslami, University of Amsterdam Department of Medical Informatics, Academic Medical Center Meibergdreef 15, J1b-124 1105 AZ Amsterdam The NetherlandsAmeen Abu-Hanna, University of Amsterdam Department of Medical Informatics, Academic Medical Center Meibergdreef 15, J1b-124 1105 AZ Amsterdam The Ne......
POSTED 06/29/2009 at 05:57 AM --

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Candida pneumonia in the ICU: myth or reality?
Content Type Journal ArticleCategory EditorialDOI 10.1007/s00134-009-1563-8Authors
Jean-Damien Ricard, Institut National de la Santé et de la Recherche Médicale (INSERM) U722 16 rue Henri Huchard 75018 Paris FranceDamien Roux, Institut National de la Santé et de la Recherche Médicale (INSERM) U722 16 rue Henri Huchard 75018 Paris France
Journal Intensive Care MedicineOnline ISSN 1432-1238Print ISSN 0342-4642 (Source: Intensive Care Medicine)...
POSTED 06/29/2009 at 05:57 AM --

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Burn-induced cerebral inflammation - a neglected entity?
Severe burn injury remains a major burden on patients and health care systems. Following severe burns, the injured tissues mount a local inflammatory response aiming to restore homeostasis. With excessive burn load, the immune response becomes disproportionate and patients may develop an overshooting systemic inflammatory response, compromising multiple physiological barriers in the lung, kidney, liver and brain. If the blood-brain barrier (BBB) is breached, systemic inflammatory molecules and phagocytes readily enter the brain and activate sessile cells of the central nervous system (CNS). Copious amounts of reactive oxygen species, reactive nitrogen species, proteases, cytokines/chemokines and complement proteins are being released by these inflammatory cells, resulting in additional neu......
POSTED 06/28/2009 at 06:00 PM --

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Prevalence of endotoxemia after surgery and its association with ICU length of stay
IntroductionThe aim of this observational study was to investigate the prevalence of endotoxemia after surgery and its association with ICU length of stay.
Methods:
102 patients admitted to a university ICU after surgery were recruited. Within four hours from admission functional data were collected and APACHE II severity score calculated. Arterial blood samples were taken and endotoxemia was measured by chemiluminescence (Endotoxin Activity [EA]). Patients were stratified according to their endotoxin levels (low, intermediate and high) and according to their surgical procedures. Differences between endotoxin levels were assessed by ANOVA, accepting P (Source: Critical Care)...
POSTED 06/28/2009 at 06:00 PM --

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Prevention of ventilator-associated pneumonia after cardiac surgery: prepare and defend!
Content Type Journal ArticleCategory EditorialDOI 10.1007/s00134-009-1522-4Authors
Patrique Segers, University of Amsterdam Departments of Cardiothoracic Surgery, Academic Medical Center Meibergdreef 9 1105 AZ Amsterdam The NetherlandsBas A. de Mol, University of Amsterdam Departments of Cardiothoracic Surgery, Academic Medical Center Meibergdreef 9 1105 AZ Amsterdam The Netherlands
Journal Intensive Care MedicineOnline ISSN 1432-1238Print ISSN 0342-4642 (Source: Intensive Care Medicine)...
POSTED 06/26/2009 at 01:56 AM --

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Interventions to decrease tube, line, and drain removals in intensive care units: the FRATER study
Conclusion UTRs are common. A continuous quality-improvement program can reduce UTR rates in the ICU.
Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s00134-009-1555-8Authors
Silvia Calvino Günther, Michallon Teaching Hospital Medical ICU BP 217 38043 Grenoble Cedex 9 FranceCarole Schwebel, Michallon Teaching Hospital Medical ICU BP 217 38043 Grenoble Cedex 9 FranceAurélien Vésin, University Joseph Fourier, Albert Bonniot Institute INSERM U823 38706 La Tronche Cedex FranceJudith Remy, Michallon Teaching Hospital Medical ICU BP 217 38043 Grenoble Cedex 9 FranceGeraldine Dessertaine, Michallon Teaching Hospital Medical ICU BP 217 38043 Grenoble Cedex 9 FranceJean-François Timsit, University Joseph Fourier, Albert Bonniot Institute INSERM U823 38706 La Tro......
POSTED 06/26/2009 at 01:56 AM --

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Incidence and risk factors for ventilator-associated pneumonia after major heart surgery
Conclusions VAP is common in patients undergoing MHS that require more than 48 h of MV. In that “high-risk” population, innovative preventive
measures should be developed and applied.
Content Type Journal ArticleCategory OriginalDOI 10.1007/s00134-009-1523-3Authors
Javier Hortal, Hospital General Universitario Gregorio Marañón Department of Anesthesia Madrid SpainMaddalena Giannella, Hospital General Universitario Gregorio Marañón Department of Clinical Microbiology and Infectious Diseases Madrid SpainMaria Jesús Pérez, Hospital General Universitario Gregorio Marañón Department of Anesthesia Madrid SpainJosé Maria Barrio, Hospital General Universitario Gregorio Marañón Department of Anesthesia Madrid SpainManuel Desco, Hospital General Universitario......
POSTED 06/26/2009 at 01:56 AM --

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Organspendebereitschaft an einer Universitätsklinik
Zusammenfassung
Hintergrund und Fragestellung Trotz aller Erfolge in der Transplantationsmedizin sterben in Deutschland jährlich etwa 1000 Patienten während der Wartezeit
auf ein geeignetes Organ. Der chronische Mangel an Spenderorganen könnte durch eine Erhöhung der Bereitschaft zur Organspende
verbessert werden. Da die Mitarbeiter der Universitätskliniken unmittelbar an der Transplantationsmedizin beteiligt sind,
ist ihre Meinung von besonderem Interesse bei der Analyse der Organspendebereitschaft.
Methodik Anfang 2007 wurde am Universitätsklinikum Essen eine Umfrage zum Thema „Organspendeausweis“ unter den Mitarbeitern durchgeführt.
Die Fragebögen waren beim Betriebsarzt ausgelegt. Die Auswertung erfolgte mittels des Fisher’s-exact- u......
POSTED 06/26/2009 at 01:00 AM --

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