Selenium Linked to Lower Bladder Cancer Risk (CME/CE)
(MedPage Today) -- The trace mineral selenium may help prevent bladder cancer, especially in women, according to a meta-analysis. (Source: MedPage Today Hematology/Oncology)...
POSTED 09/01/2010 at 02:01 PM --
|
ORIGINAL ARTICLE: Evaluation of three commercial ELISA kits for anticardiolipin and antiâbeta2âglycoprotein I antibodies in the laboratory diagnosis of the antiphospholipid syndrome
(Source: Clinical and Laboratory Haematology)...
POSTED 09/01/2010 at 01:25 AM --
|
Jack Aiello named IMF Advocate of the Month!!
Congratulations and THANK YOU to Jack Aiello, support group leader and patient from the Bay area for being this month's Advocate of the Month! (Source: International Myeloma Foundation)...
POSTED 08/31/2010 at 11:00 PM --
|
Preventive Surgery Works for BRCA Mutation Carriers (CME/CE, with video)
(MedPage Today) -- Prophylactic surgery can reduce the high risk of breast and ovarian cancer among BRCA mutation carriers and can actually improve survival, researchers affirmed. (Source: MedPage Today Hematology/Oncology)...
POSTED 08/31/2010 at 10:13 PM --
|
Editorial Board
(Source: Thrombosis Research)...
POSTED 08/31/2010 at 06:00 PM --
|
ENERCA clinical recommendations for disease management and prevention of complications of sickle cell disease in children
(Source: American Journal of Hematology)...
POSTED 08/31/2010 at 06:00 PM --
|
Efficacy of Cytokine Removal by Plasmadiafiltration Using a Selective Plasma Separator: In Vitro Sepsis Model
(Source: Therapeutic Apheresis and Dialysis)...
POSTED 08/31/2010 at 06:00 PM --
|
Review of Helicobacter pylori Infection and Chronic Renal Failure
(Source: Therapeutic Apheresis and Dialysis)...
POSTED 08/31/2010 at 06:00 PM --
|
Association Between PlateletâRelated Hemostasis Impairment and Functional Iron Deficiency in Hemodialysis Patients
(Source: Therapeutic Apheresis and Dialysis)...
POSTED 08/31/2010 at 06:00 PM --
|
BEAT CANCER TO THE FINISH LINE!Thank you to all IMFers who voted for our entry, designed by patient Keith May, in the Sponsafier 2 NASCAR design contest! We?ll find out if we?ve made the semi-final round on September 13.
Log on and vote for "The Survivor!" (Source: International Myeloma Foundation)...
POSTED 08/30/2010 at 11:00 PM --
|
Synchronous occurrence of acute promyelocytic leukemia and non-Hodgkin lymphoma
Content Type Journal ArticleDOI 10.1007/s00277-010-1053-7Authors
Wen Wang, Department of Hematology, Qilu Hospital, Shandong University, 107 West Wenhua Road, Jinan, Shandong 250012, Peopleâs Republic of ChinaYuan Yu, Department of Hematology, Qilu Hospital, Shandong University, 107 West Wenhua Road, Jinan, Shandong 250012, Peopleâs Republic of ChinaJun Peng, Department of Hematology, Qilu Hospital, Shandong University, 107 West Wenhua Road, Jinan, Shandong 250012, Peopleâs Republic of ChinaYan Shi, Department of Hematology, Qilu Hospital, Shandong University, 107 West Wenhua Road, Jinan, Shandong 250012, Peopleâs Republic of ChinaChuanfang Liu, Department of Hematology, Qilu Hospital, Shandong University, 107 West Wenhua Road, Jinan, Shandong 250012, Peopleâs Republic of Chi......
POSTED 08/27/2010 at 12:12 PM --
|
Severe congenital neutropenia in a multigenerational family with a novel neutrophil elastase (ELANE) mutation
Abstract We have analysed a family with nine congenital neutropenia patients in four generations, several of which we have studied
in a long-term follow-up of over 25 years. The patients were mild to severe neutropenic and suffered from various recurrent
bacterial infections. Mutations in the genes ELANE, CSF3R and GFI1 have been reported in patients with autosomal dominant congenital neutropenias. Using a small-scale linkage analysis with
markers around the ELANE, CSF3R, CSF3 and GFI1 genes, we were able to determine that the disease segregated with markers around the ELANE gene. We identified a novel mutation in the ELANE gene in all of the affected family members that was not present in any of the healthy family members. The mutation leads
to an A28S missense mutatio......
POSTED 08/27/2010 at 12:12 PM --
|
Overdose with 16,000mg of imatinib mesylate
We report on a 53 years old woman, who ingested 16,000mg in a suicide attempt. (Source: Leukemia Research)...
POSTED 08/27/2010 at 01:28 AM --
|
B-cell acute lymphoblastic leukemia as evolution of a 8p11 myeloproliferative syndrome with t(8;22)(p11;q11) and BCR-FGFR1 fusion gene
Rearrangement of fibroblast growth factor receptor 1 (FGFR1) gene, mapped on chromosome band 8p11, is the genetic hallmark of a rare atypical chronic myeloproliferative disorder that is usually characterized by myeloid hyperplasia, eosinophilia and high incidence of T-lymphoblastic lymphoma referred as 8p11 myeloproliferative syndrome (EMS) . (Source: Leukemia Research)...
POSTED 08/27/2010 at 01:28 AM --
|
ABVD associated with imatinib for coexisting chronic myeloid leukaemia and relapsed Hodgkin lymphoma
A 30-year-old Caucasian male has been referred to our institution in June 2009 because for 3 months he presented recurrent fever, night sweats and asthenia. Nine years before the patient has been diagnosed with nodular sclerosis classical HL; at that time a computer tomography (CT) scan demonstrated a mediastinal bulky, epatho-splenomegaly and multiple liver lesions; the diagnosis was performed on specimens obtained from mediastinal mass. Bilateral bone marrow biopsy was negative for HL involvement. The stage was defined as IV B. He was treated from November to July 2000 with eight cycles according to ABVD schedule (doxorubicin, bleomycin, vinblastine and dacarbazine) achieving a complete remission (CR). The patient remained in good clinical condition until March 2009, and did not present ......
POSTED 08/27/2010 at 01:28 AM --
|
Is there still a role for G-banding in CLL?
Chronic lymphocytic leukemia (CLL) is a lymphoproliferative disorder characterized by progressive monomorphic lymphocytosis caused by clonal accumulation of CD5+ CD19+ B cells in peripheral blood, bone marrow and lymphoid organs . Clinical course is heterogeneous. Molecular and biologic factors have been found to be useful predictors of response to treatment and survival among newly diagnosed patients. Immunoglobulin heavy chain gene mutation status, ZAP-70 and interphase cytogenetics are established risk factors . (Source: Leukemia Research)...
POSTED 08/27/2010 at 01:28 AM --
|
Facilitating studies of cell proliferation in chronic lymphocytic leukemia
We read with interest the report by Hayes et al., âIsolation of malignant B cells from patients with chronic lymphocytic leukemia (CLL) for analysis of cell proliferation: Validation of a simplified method suitable for multi-center clinical studies.â The authors describe helpful developments for analyzing in vivo proliferation rates of leukemic cells in patients with CLL. They rightly point out that, to be useful, â⦠this technology must have improved ease of use for patients, providers and researchers alikeâ and their proposed developments do indeed contribute towards this goal by introducing simpler protocols for blood collection, separation and analysis. (Source: Leukemia Research)...
POSTED 08/27/2010 at 01:28 AM --
|
Sorafenib induces sustained molecular remission in FLT3-ITD positive AML with relapse after second allogeneic stem cell transplantation without exacerbation of acute GVHD: A case report
Relapsed acute leukemia after allogeneic stem cell transplantation (SCT) has a very poor prognosis and treatment still remains a challenge . Infections and/or severe acute GvHD often preclude conventional myeloablative chemotherapy. Cellular therapies with donor lymphocyte infusions (DLI) or a second allogeneic SCT do not induce stable remissions in the majority of high-risk AML patients . (Source: Leukemia Research)...
POSTED 08/27/2010 at 01:28 AM --
|
A case of blast clearance on sorafenib in relapsed FLT3-ITD acute myeloid leukemia: Evidence of efficacy continues to mount
We present a case of sorafenib use in relapsed FLT3-ITD positive AML which supports both the in vitro finding and the in vivo efficacy demonstrated in the German report. (Source: Leukemia Research)...
POSTED 08/27/2010 at 01:28 AM --
|
Localized graft-versus-host disease of the skin provoked by radiotherapy
In multiple myeloma allogeneic stem cell transplantation (allo-SCT) is associated with the highest rate of molecular remissions and a lower risk of recurrence compared with other treatment options including autologous SCT . This is due to the graft-versus-myeloma effect, which was proven by the achievement of sustained complete remissions by donor lymphocyte infusions (DLIs) without any other therapy in patients with relapse after both myeloablative and non-myeloablative allo-SCT . However, because of high treatment-related mortality especially after myeloablative conditioning and the introduction of novel agents such as bortezomib and the immunomodulatory drugs thalidomide and lenalidomide, the value of this approach remains to be determined in clinical trials. (Source: Leukemia Research)...
POSTED 08/27/2010 at 01:28 AM --
|
