Food Allergy or Food Intolerance? A Clinical Scenario Involving Abdominal Complaints
A Clinical Practice article in the September issue of CGH looks at a scenario of a 41-Year-Old woman with complaints of intermittent nonbloody diarrhea, abdominal cramping, and bloating. (Source: Clinical Gastroenterology and Hepatology)...
POSTED 09/01/2010 at 07:42 PM --
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Poorer Outcomes Confirmed in Clopidogrel Users on Concurrent PPI
Patients starting on clopidogrel double their risk of an MI over the next few months if they take a proton pump inhibitor (PPI) at the same time, according to a large Dutch cohort study. Reuters Health Information (Source: Medscape Gastroenterology Headlines)...
POSTED 09/01/2010 at 05:20 PM --
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Advanced Endoscopic Imaging Rarely Misses Early Neoplasia in Barrett's Esophagus
Advanced endoscopic imaging rarely misses early neoplasia in patients with Barrett's esophagus, but random biopsies should not be abandoned, researchers from Germany report in the July 27th American Journal of Gastroenterology online. Reuters Health Information (Source: Medscape Gastroenterology Headlines)...
POSTED 09/01/2010 at 05:20 PM --
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Gastrointestinal Endoscopy: September 2010, Vol. 72, Issue 3
GIE audio presents the abstracts from the September issue's original articles for your listening pleasure. (Source: Gastrointestinal Endoscopy)...
POSTED 09/01/2010 at 07:00 AM --
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Liver Biopsy in the Assessment of Medical Liver Disease
(Source: NLH - Gastroenterology and Liver Diseases - Events)...
POSTED 09/01/2010 at 01:19 AM --
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Specialty Skills in Coloproctology Stage 2
(Source: NLH - Gastroenterology and Liver Diseases - Events)...
POSTED 09/01/2010 at 01:19 AM --
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Behind the headlines - Genetic effects of vitamin D studied
âStocking up on vitamin D supplements and enjoying the summer sun could cut the risk of a host of diseases,â reported the Daily Mail. This news story is based on a study that investigated how vitamin D might influence the risk of certain diseases by affecting the activity of genes. It found that vitamin D binds directly to genes associated with several common autoimmune diseases, including multiple sclerosis, type 1 diabetes, rheumatoid arthritis and colorectal cancer. Studies of this kind add to our knowledge of the function of vitamin D, and will be used to assess the guidelines for recommended vitamin D intake. What does NHS Choices make of this study? This is a valuable addition to our knowledge of the effects of vitamin D in the cells and how it might affect our risk of certain di......
POSTED 09/01/2010 at 01:19 AM --
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Behind the headlines - Stem cells converted to liver cells
You will be able to âgrow your own transplant liver in a lab within just five yearsâ, says the Daily Mail. This news story is based on research that demonstrated a method to develop skin cells into stem cells, which were then matured into liver cells. The researchers used this technique to develop lab-grown liver cells from patients with various inherited liver diseases, which they hope might aid future research into diseases. They found that the new liver cells shared a number of characteristics with the liver cells of the patients. The method developed in this research looks likely to be an invaluable technique for creating cell cultures that could be experimented on in the lab. However, this research did not aim to investigate how a fully-functional liver or transplantable cells cou......
POSTED 09/01/2010 at 01:18 AM --
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Imatinib for the adjuvant treatment of gastrointestinal stromal tumours
Aims: This guidance considers the use of imatinib for the adjuvant treatment of gastrointestinal stromal tumours. Recommendations: Imatinib is not recommended for the adjuvant treatment of gastrointestinal stromal tumours (GISTs) after surgery. People currently receiving imatinib for the adjuvant treatment of gastrointestinal stromal tumours after surgery should have the option to continue treatment until they and their clinician consider it appropriate to stop. Intended audience: Healthcare professionals. Methodology and Development: Section 4 'Consideration of the evidence' addresses the use of imatinib for the adjuvant treatment of gastrointestinal stromal tumours, and considers the findings of the evidence review group. (See also Appendix B of the guidance which outlines the sources of......
POSTED 09/01/2010 at 01:18 AM --
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Imatinib for the adjuvant treatment of gastrointestinal stromal tumours
Aims: This guidance considers the use of imatinib for the adjuvant treatment of gastrointestinal stromal tumours. Recommendations: Imatinib is not recommended for the adjuvant treatment of gastrointestinal stromal tumours (GISTs) after surgery. People currently receiving imatinib for the adjuvant treatment of gastrointestinal stromal tumours after surgery should have the option to continue treatment until they and their clinician consider it appropriate to stop. Intended audience: Healthcare professionals. Methodology and Development: Section 4 'Consideration of the evidence' addresses the use of imatinib for the adjuvant treatment of gastrointestinal stromal tumours, and considers the findings of the evidence review group. (See also Appendix B of the guidance which outlines the sources of......
POSTED 09/01/2010 at 01:18 AM --
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TLRs in Hepatic Cellular Crosstalk
Toll-like receptors (TLRs) are expressed on all major subsets of liver cells. Both exogenous ligands derived from pathogens, and endogenous ligands that are products of cellular injury, engage these receptors and activate aspects of innate immunity. These receptors play a role in viral and parasitic infections of the liver, in ischemia-reperfusion injury, and in toxic liver damage, promoting antipathogen immunity but also hepatocellular injury and fibrogenesis. However, TLRs may also participate in negative feedback that limits tissue injury. In the complex environment of the liver, TLRs participate in pathologic cascades involving multiple cell types, manifesting their effects both through cell-autonomous actions, and via cellular crosstalk. In this paper we survey the involvement of TLRs......
POSTED 09/01/2010 at 01:18 AM --
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The Use of Green Coffee Extract as a Weight Loss Supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials
The purpose of this paper is to assess the efficacy of green coffee extract (GCE) as a weight loss supplement, using data from human clinical trials. Electronic and nonelectronic searches were conducted to identify relevant articles, with no restrictions in time or language. Two independent reviewers extracted the data and assessed the methodological quality of included studies. Five eligible trials were identified, and three of these were included. All studies were associated with a high risk of bias. The meta-analytic result reveals a significant difference in body weight in GCE compared with placebo (mean difference: −2.47 kg; 95%CI: −4.23, −0.72). The magnitude of the effect is moderate, and there is significant heterogeneity amongst the studies. It is c......
POSTED 09/01/2010 at 01:18 AM --
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Celiac patients have similar colorectal neoplasia risk to general population
Study findings confirm that celiac disease patients have a similar risk for colorectal cancer to the general population. (Source: MedWire News - Gastroenterology)...
POSTED 09/01/2010 at 01:16 AM --
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Behind the headlines - Genetic effects of vitamin D studied
âStocking up on vitamin D supplements and enjoying the summer sun could cut the risk of a host of diseases,â reported the Daily Mail. This news story is based on a study that investigated how vitamin D might influence the risk of certain diseases by affecting the activity of genes. It found that vitamin D binds directly to genes associated with several common autoimmune diseases, including multiple sclerosis, type 1 diabetes, rheumatoid arthritis and colorectal cancer. Studies of this kind add to our knowledge of the function of vitamin D, and will be used to assess the guidelines for recommended vitamin D intake. What does NHS Choices make of this study? This is a valuable addition to our knowledge of the effects of vitamin D in the cells and how it might affect our risk of certain di......
POSTED 09/01/2010 at 12:57 AM --
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Cirrhosis Outcomes Better When Tx Guidelines Followed (CME/CE)
(MedPage Today) -- Routinely screening liver cirrhosis patients for esophageal varices and treating them according to published guidelines led to lower-than-expected rates of subsequent variceal hemorrhage, researchers found. (Source: MedPage Today Gastroenterology)...
POSTED 08/31/2010 at 10:13 PM --
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Realâtime tool to display the predicted disease course and treatment response for children with Crohn's disease
(Source: Inflammatory Bowel Diseases)...
POSTED 08/31/2010 at 06:00 PM --
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Information for Authors and Readers
Clinical Gastroenterology and Hepatology is the go-to resource on a broad spectrum of themes in clinical gastroenterology and hepatology. The official clinical practice journal of the AGA Institute brings you the best original research in the field with a unique combination of reviews, editorials, podcasts, video abstracts, and outcomes researchâall supporting clinical practice. Articles on education, policy, and practice management highlight issues pertinent to clinicians. (Source: Clinical Gastroenterology and Hepatology)...
POSTED 08/31/2010 at 06:00 PM --
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Contents
(Source: Clinical Gastroenterology and Hepatology)...
POSTED 08/31/2010 at 06:00 PM --
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Editorial Board
(Source: Clinical Gastroenterology and Hepatology)...
POSTED 08/31/2010 at 06:00 PM --
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Cover
(Source: Clinical Gastroenterology and Hepatology)...
POSTED 08/31/2010 at 06:00 PM --
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