Immunovaccine Presents Results For An Enhanced Anthrax Vaccine Candidate
Immunovaccine Inc. (TSX VENTURE:IMV) announced that it has been invited to present at the Canada - U.S. Partners in Biomedical Defense II Conference in Washington, D.C. on Wednesday, February 10, 2010... (Source: Immune System / Vaccines News From Medical News Today)...
POSTED 02/09/2010 at 03:00 AM --

|
GeoVax Labs, Inc. Begins Enrollment At Final Site For Preventative Vaccine; Next Step Is To Submit IND Application For Therapeutic Vaccine To FDA
GeoVax Labs, Inc. (OTC Bulletin Board: GOVX) (the "Company"), an Atlanta-based, biopharmaceutical company developing human vaccines for diseases caused by HIV-1 (Human Immunodeficiency Virus) and other infectious agents, provided an update on its vaccine trials progress... (Source: Immune System / Vaccines News From Medical News Today)...
POSTED 02/09/2010 at 03:00 AM --

|
NOVAVAX Reports Additional Positive Data From Its Trivalent Seasonal Influenza (VLP) Vaccine Clinical Study In Healthy Adults
Novavax, Inc. (Nasdaq: NVAX) announced new data from a clinical study that began in May of 2009 among healthy adults 18 to 49 years of age with Novavax's trivalent seasonal influenza Virus-like Particle (VLP) vaccine. The vaccine matched the influenza strains recommended for the 2008-2009 influenza season including H1N1 A/Brisbane/59/2007, H3N2 A/Brisbane/10/2007, and B/Florida/04/2006 strains... (Source: Immune System / Vaccines News From Medical News Today)...
POSTED 02/09/2010 at 03:00 AM --

|
Dana-Farber And Sanford-Burnham Institute License Flu-Targeting Antibodies
Dana-Farber Cancer Institute and the Sanford-Burnham Medical Research Institute have signed a license agreement with Genentech, a wholly owned member of the Roche group, and Roche, that grants the companies exclusive rights to manufacture, develop and market human monoclonal antibodies to treat and protect against group 1 influenza viruses... (Source: Immune System / Vaccines News From Medical News Today)...
POSTED 02/09/2010 at 02:00 AM --

|
Identification of a novel HLA class I allele, HLA-Cw*0134 in a Chinese individual
The new human leukocyte antigen (HLA) class I allele, HLA-Cw*0134, was identified in a Chinese individual. HLA-Cw*0134 differs from HLA-Cw*0124 by one nonsynonymous nucleotide change at the codon 99 (TGT to TAT) and one synonymous nucleotide change at the codon 127 (AAC to AAT). (Source: Tissue Antigens)...
POSTED 02/08/2010 at 06:00 PM --

|
Human platelet antigen allele frequencies in different Algerian populations
This study is the first to report on HPA allele frequencies in Algerian populations. High allele frequencies were observed for HPA-1b (0.209[ndash]0.112), HPA-3b (0.411[ndash]0.312) and HPA-5b (0.217[ndash]0.087), leading to a high risk of alloimmunization in this population, especially the Mzab and the population of Annaba. Our results could have some impact in the diagnosis, prevention and treatment of alloimmune thrombocytopenia. (Source: Tissue Antigens)...
POSTED 02/08/2010 at 06:00 PM --

|
A new allele, HLA-G*010120, is generated by a recombination event between HLA-G*01010101/02 and HLA-G*01010201
Recombination between HLA-G*01010101/02 and HLA-G*01010201 generates HLA-G*010120. (Source: Tissue Antigens)...
POSTED 02/08/2010 at 06:00 PM --

|
The Effect of High Gravidity on the Carcinogenesis of Mammary Gland in TA2 Mice
Citation Wang X, Huang C, Sun B, Gu Y, Cui Y, Zhao X, Li Y, Zhang S. The effect of high gravidity on the carcinogenesis of mammary gland in TA2 mice. Am J Reprod Immunol 2010 Spontaneous breast cancer in Tientsin Albinao 2 (TA2) mice, like human pregnancy-associated breast cancer (PABC), often occurs in pregnancy and puerperium, especially in mice with high gravidity. We hypothesized that the dysfunction of cellular immunity caused by the increase of 17[beta]-estradiol (E2) and progesterone (P) might be one of the reasons for carcinogenesis of mammary gland. We investigated the T lymphocyte subsets and the concentration of serum hormone and cytokines in cancer-bearing, pregnant or postpartum TA2 mice using flow cytometry, chemiluminescent immunoassay, and enzyme-linked immunosorbent assay ......
POSTED 02/08/2010 at 06:00 PM --

|
Chief Medical Officer Mobilises GPs To Support Pandemic (H1N1) 2009 Influenza Vaccinations
Australia's Chief Medical Officer, Professor Jim Bishop, is calling on GPs to promote vaccination against the pandemic (H1N1) 2009 influenza to their patients before the flu season begins in Australia ... (Source: Immune System / Vaccines News From Medical News Today)...
POSTED 02/08/2010 at 06:00 AM --

|
Talecris Biotherapeutics Receives Orphan Drug Designation For Aerosolized Alpha1-Proteinase Inhibitor To Treat Alpha1-Antitrypsin Deficiency
Talecris Biotherapeutics, Inc. (Nasdaq: TLCR) announced that it was granted orphan drug designation by the U.S. Food and Drug Administration (FDA) for the development of an aerosol formulation of Alpha1-Proteinase Inhibitor (Human, A1PI) to treat congenital alpha1-antitrypsin (AAT) deficiency... (Source: Immune System / Vaccines News From Medical News Today)...
POSTED 02/08/2010 at 05:00 AM --

|
Today's Opinions And Editorials
Pfizer's Bad Political Bet The Wall Street Journal The sight of ObamaCare on life support has many Democrats disappointed. It could be worse. They could be Pfizer CEO Jeffrey Kindler (Kimberley Strassel, 2/4). The Verizon Wireless Cure The Christian Science Monitor Are health insurance company employees just meaner and more greedy than those who provide cellphone service ... (Source: Immune System / Vaccines News From Medical News Today)...
POSTED 02/08/2010 at 04:00 AM --

|
Poll Finds That Nearly Half Of Americans Believe H1N1 Outbreak Is Over
The latest poll from researchers at the Harvard School of Public Health (HSPH) shows that almost half of Americans believe the H1N1 flu outbreak is over (44%), and levels of concern about getting sick with the virus continue to decline. Few (18%) think it is "very likely" there will be another widespread outbreak of the H1N1 virus in the U.S... (Source: Immune System / Vaccines News From Medical News Today)...
POSTED 02/08/2010 at 03:00 AM --

|
Site-directed mutagenesis reveals a unique requirement for tyrosine residues in IL-7R alpha and TSLPR cytoplasmic domains in TSLP-dependent cell proliferation
Conclusion:
These results suggest that TSLP requires at least one cytoplasmic tyrosine residue to transmit proliferative signals. Unlike other members of IL-2 cytokine family, tyrosine residues in IL-7R alpha and TSLPR cytoplasmic domains play a redundant role in TSLP-mediated cell growth. (Source: BMC Immunology)...
POSTED 02/07/2010 at 06:00 PM --

|
Risk of first-generation H1-antihistamines: a GA2LEN position paper
Conclusions: This review raises the issue of better consumer protection by recommending that older first-generation H1-antihistamines should no longer be available over-the-counter as prescription- free drugs for self-medication of allergic and other diseases now that newer second- generation nonsedating H1-antihistamines with superior risk/benefit ratios are widely available at competitive prices. (Source: Allergy)...
POSTED 02/07/2010 at 06:00 PM --

|
Improving clinician–patient communication in asthma: the HARP project
(Source: Allergy)...
POSTED 02/07/2010 at 06:00 PM --

|
Lifestyle and parental allergen sensitization are reflected in the intrauterine environment at gene expression level
Conclusion: Living on a farm and parental allergen sensitization are reflected in the intrauterine environment at the gene expression level. (Source: Allergy)...
POSTED 02/07/2010 at 06:00 PM --

|
Importance of cytokines in murine allergic airway disease and human asthma.
Authors: Finkelman FD, Hogan SP, Hershey GK, Rothenberg ME, Wills-Karp M
Asthma is a common, disabling inflammatory respiratory disease that has increased in frequency and severity in developed nations. We review studies of murine allergic airway disease (MAAD) and human asthma that evaluate the importance of Th2 cytokines, Th2 response-promoting cytokines, IL-17, and proinflammatory and anti-inflammatory cytokines in MAAD and human asthma. We discuss murine studies that directly stimulate airways with specific cytokines or delete, inactivate, neutralize, or block specific cytokines or their receptors, as well as controversial issues including the roles of IL-5, IL-17, and IL-13Ralpha2 in MAAD and IL-4Ralpha expression by specific cell types. Studies of human asthmatic cytokine gene an......
POSTED 02/06/2010 at 11:12 AM --

|
QIAGEN Unit And Pfizer Enter Into An Agreement To Develop A Companion Diagnostic For Brain Tumor Patients
Pfizer Inc. (NYSE: PFE) and DxS (a wholly owned subsidiary of QIAGEN N.V.) (NASDAQ: QGEN; Frankfurt, Prime Standard: QIA) announced that they have entered into an agreement to develop a companion diagnostic test kit for PF-04948568 (CDX-110), an immunotherapy vaccine in development for the treatment of glioblastoma multiforme (GBM)... (Source: Immune System / Vaccines News From Medical News Today)...
POSTED 02/06/2010 at 04:00 AM --

|
PharmAthene Submits White Paper To BARDA For Advanced Development Funding For SparVax(TM) - Novel Recombinant Protective Antigen Anthrax Vaccine
PharmAthene, Inc... (Source: Immune System / Vaccines News From Medical News Today)...
POSTED 02/06/2010 at 03:00 AM --

|
NTU Researchers Complete The World's First In-depth Study Of The Malaria Parasite Genome
Groundbreaking research done at Nanyang Technological University's (NTU) School of Biological Sciences (SBS) could lead to the development of more potent drugs or a vaccine for malaria, which is transmitted to humans by infected mosquitoes and kills up to three million people each year... (Source: Immune System / Vaccines News From Medical News Today)...
POSTED 02/06/2010 at 03:00 AM --

|