Novartis and collaborators discover novel antimalarial drug candidate
(Novartis Institutes for BioMedical Research) Published this week in Science the findings demonstrate that the antimalarial candidate, spiroindolone NITD609, is effective against both strains of the malaria parasite, Plasmodium (P.) falciparum and P. vivax. Through a novel mechanism NITD609 rapidly clears plasmodium in a malaria mouse model and shows pharmacological properties compatible with a once-daily dosing regimen....
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Children who eat vended snack foods face chronic health problems, poor diet
(University of Michigan Health System) School children who consume foods purchased in vending machines are more likely to develop poor diet quality -- and that may be associated with being overweight, obese or at risk for chronic health problems such as diabetes and coronary artery disease, according to research from the University of Michigan Medical School....
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American Society for Biochemistry and Molecular Biology reacts to stem-cell ruling
(American Society for Biochemistry and Molecular Biology) The American Society for Biochemistry and Molecular Biology expressed its disapproval and disappointment this week in response to the Aug. 23 court ruling that temporarily bars federal funding of embryonic stem-cell research....
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New model may simplify high-dose radiosurgery planning
(Ohio State University Medical Center) There is yet no straightforward way to determine the optimal dose level and treatment schedules for high-dose radiation therapies such as stereotactic radiation therapy, which is used to treat brain and lung cancer, or for high-dose brachytherapy for prostate and other cancers. Radiation oncology researchers at Ohio State University may have solved the problem with a new mathematical model called the Generalized LQ (gLQ) Model that encompasses all dose levels and schedules...
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Cigarette smoke may contribute to lung inflammation through a new chemical pathway
(University of Alabama at Birmingham) Cigarette smoke shuts off a key enzyme in airways that regulates the body's response to inflammation, according to findings from the University of Alabama at Birmingham published online today at Science Express. The UAB researchers say smoke inhibits the enzyme, called Leukotriene A4 Hydrolase (LTA4H), causing it to fail in its job of shutting down white blood cells following a successful response to inflammation....
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UCSF unveils model for implantable artificial kidney to replace dialysis
(University of California - San Francisco) UCSF researchers today unveiled a prototype model of the first implantable artificial kidney, in a development that one day could eliminate the need for dialysis....
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LSUHSC pediatric weight expert provides obesity trinity answers
(Louisiana State University Health Sciences Center) In a first person paper published in the Aug. 27, 2010 issue of Childhood Obesity, Dr. Melinda Sothern, Director of Health Promotion and Professor of Public Health at LSU Health Sciences Center New Orleans, provides three ways to de-program the 1950s obesity trinity underlying the current obesity epidemic in the United States and protect future generations from its health consequences....
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University at Buffalo symposium on in silico methods, high throughput screening
(University at Buffalo) Twenty-first century drug discovery tools, including those targeted to develop new treatments for cancer and hereditary eye diseses, will be featured at "Twenty-first Century Bioscience: In Silico Methods and High-Throughput Screening," a University at Buffalo symposium on Sept. 11. The symposium will be held at the Hauptman-Woodward Medical Research Institute, 700 Ellicott St., Buffalo from 8:30 a.m. to 5 p.m....
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Test-tube calf embryos more likely to survive Texas summers
(Texas A&M AgriLife Communications) Texas AgriLife researchers have found that embryo transfer can double dairy cow pregnancy rates during the summer and increase the number of heifers born as compared with conventional artificial insemination commonly used on dairy farms. They believe this method could save dairies in Texas and throughout the country considerable money....
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Scientists identify molecules involved in touch and other mechanically activated systems
(Scripps Research Institute) Scripps Research Institute scientists have identified two proteins with potential to be important targets for research into a wide range of health problems, including pain, deafness, and cardiac and kidney dysfunction....
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GEN reports on the greening of the life sciences
(Mary Ann Liebert, Inc./Genetic Engineering News) Biopharmaceutical firms and other life science organizations are taking definitive steps toward creating greener working environments and developing more sustainable operations, reports Genetic Engineering & Biotechnology News. This promising trend was made clear through a series of presentations and panel discussions that took place at GEN's "GreenBioPharma" conference, which was recently held in Philadelphia....
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SRNL, Chernobyl Laboratory collaborate on research initiatives
(DOE/Savannah River National Laboratory) Under a recently signed agreement, the US Department of Energy's Savannah River National Laboratory and the Ukraine's International Radioecology Laboratory will collaborate on radiation ecology research, including projects in the region impacted by the catastrophic accident at the Chernobyl Nuclear Power Plant 24 years ago....
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Edible nanostructures
(Northwestern University) Sugar, salt, alcohol and a little serendipity led Northwestern University researchers to discover a new class of nanostructures that could be used for gas storage and food and medical technologies. And the compounds are edible. The porous crystals are the first known all-natural metal-organic frameworks (MOFs) that are simple to make. Most other MOFs are made from petroleum-based ingredients, but the Northwestern MOFs you can pop into your mouth and eat, and the researchers have....
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K-State research project offers insight into superstitious behavior
(Kansas State University) People who believe that fate and chance control their lives are more likely to be superstitious -- but when faced with death they are likely to abandon superstition altogether, according to a recent Kansas State University undergraduate research project....
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Moussa B.H. Youdim wins the 2010 ECNP Lifetime Achievement Award
(European College of Neuropsychopharmacology) The European College of Neuropsychopharmacology is pleased to announce Moussa B. H. Youdim as the recipient of the 2010 ECNP Lifetime Achievement Award in recognition of his innovative and lasting contribution to the area of neurodegenerative diseases and neuropsychiatric drug development. The ECNP Lifetime Achievement Award is presented biennially and recognises significant and lasting impact on the field of neuropsychopharmacology. The award is accompanied by a prize of 20,000 ($25,600)....
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Hormel Institute study reveals capsaicin can act as cocarcinogen
(University of Minnesota) The September cover story of the nation's leading cancer journal, Cancer Research, features a new study from the Hormel Institute, University of Minnesota, that links capsaicin, a component of chili peppers, to skin cancer....
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Safety cultures in EMS agencies vary widely, Pitt study finds
(University of Pittsburgh Schools of the Health Sciences) A survey of emergency medical services agencies from across the country found wide variation in perceptions of workplace safety culture -- providing a tool that might point to potential patient safety threats, according to researchers at the University of Pittsburgh School of Medicine....
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Water management and malnutrition crucial issues at McGill food conference
(McGill University) Water management and malnutrition are the two key threats to food security that will be discussed at the Third McGill Conference on Global Food Security, to be held Oct. 19-21, 2010, in Montreal....
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EMAS publishes position statements about the post-reproductive health of women
(Elsevier) Statements, published in the journal Maturitas, cover the management of the menopause in the context of obesity, epilepsy, endometriosis and premature ovarian failure....
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American Chemical Society Webinar focuses on providing scientific advice to the film industry
(American Chemical Society) News media and others interested in the chemical sciences are invited to join the next in a series of American Chemical Society Webinars, focusing on opportunities for scientists to consult for the film industry. Scheduled for Thursday, September 9, from 2-3 p.m. EDT, the free ACS Webinar features Barry J. Byrne, M.D., Ph.D., of the University of Florida, speaking on "How Scientific Skills are Used in Advising the Movie Industry -- Facts and Fiction"....
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