Anal carcinoma in HIV-positive men: results of a prospective study from Germany.
Conclusions Anal carcinoma and AIN are frequent in HIV-positive men, even in patients participating in anal cancer prevention programs. High-grade dysplasia in these patients can progress to invasive cancer within a short period of time. Anal margin carcinoma and anal canal carcinoma substantially differ in their lesional HPV-spectrum, prognosis, and treatment response.
PMID: 20184584 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)...
POSTED 02/21/2010 at 06:00 PM --
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Comparison of a modified anoscope and the purse-string anoscope in stapled haemorrhoidopexy.
CONCLUSION: Operation time decreased and the surgeon's satisfaction increased with use of the modified anoscope, and fewer haemostatic sutures were required if the surgeon waited longer before and after firing the stapler.
PMID: 19938197 [PubMed - as supplied by publisher] (Source: World Journal of Gastroenterology : WJG)...
POSTED 11/26/2009 at 07:54 AM --
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Anal-rectal cytology: A review
The incidence of invasive anal squamous cell carcinoma, a human papilloma virus (HPV) related cancer, is on the rise, especially in HIV positive men who have sex with men (MSM). Like cervical cancer, anal cancer is associated with precursor lesions detectable on exfoliative cytology as squamous intraepithelial lesions and on biopsy as intraepithelial neoplasia. Anal-rectal cytology screening programs, similar to cervical cytology screening programs, have been developed in an effort to detect and to eradicate precursor lesions prior to progression to invasive squamous cell carcinoma. Either conventional or liquid-based anal-rectal cytology specimens are acceptable, but liquid-based specimens are preferred. Specimens may be collected by health care professionals or by patients. A minimum of ......
POSTED 11/24/2009 at 06:00 PM --
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Anal cytology in patients with AIDS
The objective of the present study was to study the prevalence of abnormal anal cytology in patients with AIDS. Anal smears, obtained with a cytobrush, of 102 HIV-positive patients of the Emilio Ribas Institute (Sao Paulo, Brazil) were collected, and only after that, the patients were submitted to anoscopy. Thirty-two patients had LSIL and 14 others had HSIL. Squamous intra-epithelial lesions were also observed in 38% of the patients without condyloma (18/47): in 9 of the 33 patients without history of condyloma (27%) and in 9 of the 14 patients who had previously treated condyloma (64%). An invasive squamous cell carcinoma was observed in one patient without history of condyloma. In all 13 patients with HSIL, biopsies guided by high resolution anoscopy confirmed high grade dysplasia. Our ......
POSTED 10/07/2009 at 06:00 PM --
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Management of Anal Squamous Intraepithelial Lesions
Clinics in Colon and Rectal Surgery 2009; 22: 094-101DOI: 10.1055/s-0029-1223840ABSTRACTAnal squamous intraepithelial lesions include both low-grade squamous intraepithelial lesions (LSIL) and high-grade squamous intraepithelial lesions (HSIL) and are caused by chronic infection with the human papillomavirus (HPV). The disease is increasing in both incidence and prevalence, especially among patients with the following risk factors: homosexual men, acquired or iatrogenic immunosuppression, and presence of other HPV-related diseases. Although the natural history of the disease is unknown, there is significant evidence that untreated HSIL progresses to squamous cell carcinoma in 11% of patients and in up to 50% of patients with extensive disease and immunosuppression. Anal cytology and reflex......
POSTED 05/28/2009 at 03:29 AM --
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High level of HPV 16 and 18 DNA load in anal swabs from male and female HIV-1 infected patients
Conclusions: Longitudinal studies are needed to evaluate the link between high anal HPV DNA load and progression to anal squamous intraepithelial lesions and anal cancer. (Source: Journal of Clinical Virology)...
POSTED 03/31/2009 at 11:00 PM --
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High level of HPV 16 and 18 DNA load in anal swabs from male and female HIV-1 infected patients.
CONCLUSIONS: Longitudinal studies are needed to evaluate the link between high anal HPV DNA load and progression to anal squamous intraepithelial lesions and anal cancer.
PMID: 19269245 [PubMed - as supplied by publisher] (Source: Journal of Clinical Virology)...
POSTED 03/04/2009 at 11:00 PM --
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[Anogenital warts: a clinical, pathological and virological study.]
The objective of this study was to investigate the possible relationship between the presence of anogenital warts (AGW) in children and the sexual abuse as mode of transmission. Our series includes 8 patients with AGW who were treated in our hospital during the year 2007. A complete physical examination was carried out, including colposcopy or anoscopy, and samples were taken for histopathological examination and human papiloma virus (HPV) subtyping. We considered perinatal transmission as a possible route in two cases. Although sexual abuse was definitively confirmed in only one case, we observed some findings in four cases that led us to consider the possibility of sexual abuse. We did not consider the possibility of heteroinoculation or autoinoculation from common warts in any case. Our......
POSTED 11/30/2008 at 11:00 PM --
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A simplified method for anal ultrasonography: assessment of patient satisfaction and the simplicity of the procedure
Conclusions This simple and less-costly adaptation of anal ultrasonography allows good quality examinations to be performed with better
patient comfort in units with echoendoscopes already available, avoiding the need for a more expensive dedicated probe.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10151-008-0422-xAuthors
D. Castellani, University of Perugia Gastroenterology and Hepatology Section Department of Clinical and Experimental Medicine Perugia ItalyE. Antonelli, University of Perugia Gastroenterology and Hepatology Section Department of Clinical and Experimental Medicine Perugia ItalyG. Sabatino, University of Perugia Gastroenterology and Hepatology Section Department of Clinical and Experimental Medicine Perugia ItalyV. Giuliano, Univer......
POSTED 08/05/2008 at 02:05 AM --
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Performing Handsewn Coloanal Anastomosis with the Pursestring Suture Anoscope
Abstract The pursestring suture anoscope, originally developed for the procedure for rectal prolapse and hemorrhoids, has been successfully
used when performing coloanal anastomosis. The use of this tool for handsewn coloanal anastomosis can achieve relatively atraumatic
results to the patient. It is a suitable and handy tool that makes handsewn transanal colonanal anastomosis simple and easy
to perform.
Content Type Journal ArticleCategory Technical NotesDOI 10.1007/s10350-008-9309-1Authors
Chih-Chien Chin, Chang Gung Memorial Hospital Division of Colon and Rectal Surgery, Department of Surgery 6 West, Chia-Pu Rd Putz City, Chiayi County TaiwanWen-Shih Huang, Chang Gung Memorial Hospital Division of Colon and Rectal Surgery, Department of Surgery 6 West, Chia-Pu Rd Putz......
POSTED 07/03/2008 at 03:05 AM --
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Videoanoscope-assisted stapled haemorrhoidopexy: analysis of 18 patients
Abstract An optimal stapled haemorrhoidopexy requires the purse-string suture to be placed circumferentially at a constant distance
from the dentate line and to pass through an appropriate thickness of rectal mucosa. An unsuitable purse-string suture may
increase the risk of postoperative complications. We developed a new anoscope (the videoanoscope) to prevent the difficulties
during application of the purse-string suture, and we used the videoanoscope in 18 stapled haemorrhoidopexy procedures. The
videoanoscope is made up of three pieces. The front part is in the form of an open half-cylinder. The second piece is a sliding
lid that covers the front piece. The rear part of the anoscope includes a hollow handle in which a scope can be inserted,
and the whole procedure can ......
POSTED 06/11/2008 at 01:08 AM --
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Management of internal genital warts: do we all agree? A postal survey
A postal survey was undertaken to determine whether there was any consensus of opinion regarding the management of internal genital warts in genitourinary medicine clinics in the UK. Overall, 110 forms were returned (57% response). The majority of clinics would refer patients with cervical warts for colposcopy especially if the patient was over the age of 25 or HIV-positive. Proctoscopy or anoscopy was performed in 60% of clinics for patients with perianal warts to determine the presence of warts within the anal canal or rectum. Only 24% of patients with intra-anal warts are referred directly to surgery for biopsy, increasing to 61% if the patient has HIV infection. Cryotherapy is the main treatment for all types of internal warts. Our findings suggest there is no consensus and we recommen......
POSTED 05/19/2008 at 11:00 PM --
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A new anoscope for transanal surgery.
CONCLUSION: Preliminary histologic studies in the pig suggest that the design of the anoscope prevents inclusion of the muscular layer in the pursestring.
PMID: 18466861 [PubMed - as supplied by publisher] (Source: American Journal of Surgery)...
POSTED 05/05/2008 at 11:00 PM --
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[Clinical] Diagnosing chlamydia and managing proctitis in men who have sex with men: current UK practice
Conclusions:
There is a wide variation in the diagnosis and management of chlamydial infection in MSM and there is an urgent need for a more consistent approach. (Source: Sexually Transmitted Infections)...
POSTED 03/26/2008 at 11:00 PM --
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High-Resolution Anoscopy Targeted Surgical Destruction of Anal High-Grade Squamous Intraepithelial Lesions: A Ten-Year Experience
Conclusions High-resolution anoscopy-targeted destruction combined with office-based surveillance and therapy is effective in controlling
high-grade squamous intraepithelial lesions and is superior to reports of expectant management or traditional mapping procedures.
Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s10350-008-9233-4Authors
Carlos E. Pineda, Stanford University School of Medicine Department of General Surgery Stanford California USAJ. Michael Berry, University of California San Francisco Department of Medicine San Francisco California USANaomi Jay, University of California San Francisco Department of Medicine San Francisco California USAJoel M. Palefsky, University of California San Francisco Department of Medicine San Francisco Cal......
POSTED 03/25/2008 at 02:16 AM --
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Validation set correlates of anogenital injury after sexual assault.
CONCLUSIONS: Approximately half the patients displayed AGI. This rate is higher than earlier studies, but consistent with current investigations utilizing similar injury detection methods. The correlates of injury found reinforce the findings of prior studies, while prompting questions for future study.
PMID: 18304053 [PubMed - in process] (Source: Accident and Emergency Nursing)...
POSTED 02/29/2008 at 02:09 PM --
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Anal Human Papillomavirus Testing with Digene’s Hybrid Capture 2 Using Two Different Sampling Methods
Conclusions Anal screening for human papillomavirus-DNA by hybrid capture 2 is a useful method for detection of human papillomavirus-associated
disease. Sample collection using Dacron swabs identifies more human papillomavirus-positive patients, and yields higher relative
light unit values than using the cervical brush. Further studies are needed to determine the exact value of hybrid capture
2 in the screening for (pre)cancerous lesions of the anal canal.
Content Type Journal ArticleCategory Original ContributionsDOI 10.1007/s10350-007-9082-6Authors
Florian Roka, Medical University Vienna Department of Dermatology, Division of General Dermatology Vienna AustriaJulia Roka, Medical University Vienna Department of Surgery Austria, Waehringer Guertel 18–20 A-1090 Vien......
POSTED 11/21/2007 at 10:41 AM --
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Perianal squamous cell carcinoma with high-grade anal intraepithelial neoplasia in an HIV-positive patient using highly active antiretroviral therapy: case report.
Authors: Nahas SC, Nahas CS, Silva Filho EV, Levi JE, Atui FC, Marques CF
CONTEXT: Highly active antiretroviral therapy (HAART) has turned human immunodeficiency virus (HIV) infection into a chronic condition, and this has led to increased incidence of anal dysplasia among HIV-positive patients. Routine anal evaluation including the anal canal and perianal area is recommended for this population, especially for patients infected by oncogenic human papillomavirus (HPV) types. CASE REPORT: A 54-year-old homosexual HIV-positive man presented with a six-year history of recurrent perianal and anal warts. He had previously undergone incomplete surgical excision and fulguration in another institution on two occasions. He had been using HAART over the past two years. He presented some condylom......
POSTED 08/31/2007 at 11:00 PM --
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High Resolution Anoscopy in the Planned Staged Treatment of Anal Squamous Intraepithelial Lesions in HIV-Negative Patients
Abstract Anal dysplasia (low-grade squamous intraepithelial lesions, LSIL; high-grade squamous intraepithelial lesions, HSIL) is a
challenging disease for the surgeon. We reviewed 42 patients that underwent high-resolution anoscopy (HRA)-targeted surgical
therapy of anal dysplasia in the past 10 years. Patients were followed up in the Anal Neoplasia Clinic with physical examination,
cytology, HRA, and biopsy if indicated. Patients with disease amenable to local therapy were treated with office-based HRA-directed
therapies. There were 30 men (mean age 39 years, range 21–63) and 12 women (mean age 50 years, range 31–71) included in the
study. HSIL was present in 33, with four undergoing planned staged treatment due to circumferential disease. HSIL recurred
......
POSTED 08/21/2007 at 01:47 AM --
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Combined Colonoscopy and Three-Quadrant Hemorrhoidal Ligation: 500 Consecutive Cases
Conclusions Combining colonoscopy with three-quadrant hemorrhoidal ligation is a safe and effective method of treating symptomatic internal
hemorrhoids. The procedure is convenient for both physician and patient and makes more efficient use of time and resources.
Content TypeJournal Article
JournalDiseases of the Colon & RectumOnline ISSN 1530-0358Print ISSN 0012-3706 (Source: Diseases of the Colon & Rectum)...
POSTED 07/31/2007 at 01:45 AM --
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