ESC: No Benefit for Lower Dose Heparin With Fondaparinux (CME/CE)
STOCKHOLM (MedPage Today) -- In patients receiving fondaparinux (Arixtra) before angioplasty, a lower dose of unfractionated heparin as an adjunct was no better than the standard dose, a randomized trial showed. (Source: MedPage Today Cardiovascular)...
POSTED 09/01/2010 at 09:04 AM --
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New 2010 ESC Guidelines For Percutaneous Coronary Interventions Reinforce Importance Of FFR In Treatment Of Coronary Artery Disease
St. Jude Medical, Inc. (NYSE:STJ) applauds the updated class and level of evidence for Fractional Flow Reserve (FFR)-guided treatment in the Guidelines on Percutaneous Coronary Intervention (PCI) announced Monday at the European Society of Cardiology (ESC) congress in Stockholm. Supporting this change are the very strong one and two year data from the landmark FAME (Fractional Flow Reserve (FFR) vs. Angiography in Multivessel Evaluation) trial, which demonstrated improved outcomes for patients with multivessel coronary artery disease whose treatment was guided by St... (Source: Health News from Medical News Today)...
POSTED 09/01/2010 at 08:00 AM --
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Angioplasty Patients Double Dosages And Reduce Heart Attack, Stroke And Death
Clopidogrel anticlotting prescription, in doubled dosages minimizes risk of cardiovascular deaths, heart attaches ad strokes by 14%. Intensified bleeding in patients did rise by 40%, but proved to show zero percent increase in coronary artery bypass graft surgery patients, intracranial bleeding or fatalities. The study conducted by Dr. Shamir Mehta, Hamilton General Hospital and McMaster University, Hamilton, ON, Canada, concludes that double-dose clopidogrel regiment can be considered for all acute coronary cases... (Source: Health News from Medical News Today)...
POSTED 09/01/2010 at 03:00 AM --
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Instantaneous coronary collateral function during supine bicycle exercise
Conclusion
In patients with non-occlusive CAD, collateral flow instantaneously doubles during supine bicycle exercise as compared with the resting state.
ClinicalTrials.gov Identifier: NCT00947050. (Source: European Heart Journal)...
POSTED 09/01/2010 at 02:09 AM --
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Cardiac care pathway: all hands to the pump
A countywide angioplasty service is speeding up recovery times through multi-trust cooperation, reports Alison Moore (Source: HSJ)...
POSTED 08/31/2010 at 07:00 PM --
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Heparin dose during PCI after initial fondaparinux treatment of ACS
Source: JAMA
Area: News
A controlled trial found no significant differences in major bleeding or complications during percutaneous coronary intervention (PCI) between low and high doses of unfractionated heparin (UFH) in patients who had been treated with fondaparinux for acute coronary syndromes (ACS).
Fondaparinux is commonly used as an antithrombotic agent in the management of patients with ACS: many of these patients will proceed to PCI, and it is recommended that UFH is used during the procedure. The most appropriate dose is, however, unclear and guidelines recommend both higher (European) and lower (US) doses: this trial aimed to determine whether there was any difference in clinical outcomes between standard dose and a fixed low dose. Participants were patients with ACS ......
POSTED 08/31/2010 at 06:00 PM --
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ESC: Double-Dose Clopidogrel May Not Benefit ACS Patients
In patients with acute coronary syndromes referred for an invasive intervention, there is no overall
difference between double-dose clopidogrel and the standard regimen, or between higher-dose and lower-dose aspirin,
for reducing cardiovascular death, myocardial infarction, or stroke, according to research published in the Sept. 2
issue of the New England Journal of Medicine. However, according to research published online Sept. 1 in The
Lancet, double-dose clopidogrel is associated with reduced cardiovascular events and stent thrombosis in patients
undergoing percutaneous coronary intervention for acute coronary syndromes. This research has been published to
coincide with the European Society of Cardiology Congress, held from Aug. 28 to Sept. 1 in Stockholm,
Sweden. (Source:......
POSTED 08/31/2010 at 06:00 PM --
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Drug trial results refine treatment during angioplasty operations
(McMaster University) A landmark international study, coordinated by McMaster University, has found that lower doses of a blood thinner called unfractionated heparin (UFH) during angioplasty did not reduce bleeding or vascular complications compared to standard dose UFH in patients initially treated with a blood thinner, fondaparinux. (Source: EurekAlert! - Medicine and Health)...
POSTED 08/30/2010 at 11:00 PM --
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ESC: Low-Dose Heparin Doesn't Reduce PCI-Related Bleeding
Compared with standard unfractionated heparin, low-dose unfractionated heparin does not appear to
reduce peri-percutaneous coronary intervention bleeding and vascular access-site complications in patients with
non-ST-segment elevation acute coronary syndromes, according to research published online Aug. 31 in the Journal of
the American Medical Association to coincide with the European Society of Cardiology Congress, held from Aug. 28 to
Sept. 1 in Stockholm, Sweden. (Source: Modern Medicine)...
POSTED 08/30/2010 at 06:00 PM --
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ESC: Novel Antiplatelet Shows Promise (CME/CE, with video)
STOCKHOLM (MedPage Today) -- An investigational P2Y12 inhibitor -- elinogrel -- resulted in faster and greater platelet inhibition and similar clinical efficacy compared with clopidogrel (Plavix) in patients undergoing elective percutaneous coronary intervention, a phase II study presented here showed. (Source: MedPage Today Cardiovascular)...
POSTED 08/30/2010 at 03:31 PM --
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Stent Implantation Linked to Blood Clot Risk in Black Patients
Race was strongest predictor of clotting after one month, study found
Source: HealthDay
Related MedlinePlus Pages: African-American Health, Angioplasty (Source: MedlinePlus Health News)...
POSTED 08/30/2010 at 03:00 PM --
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ATOLL Study Results With Intravenous Enoxaparin in Acute Heart Attack Managed with Urgent Angioplasty
PARIS, August 30, 2010/PRNewswire/ --
Â
- Composite Primary Endpoint: Risk Reduction of 17%
(Non-Statistically Significant ) in Death, Complication of
Myocardial Infraction, Procedure Failure or Major Bleeding
(p=0.07)
Â
- Main Secondary... (Source: Drugs.com - Clinical Trials)...
POSTED 08/30/2010 at 02:08 PM --
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Low-Dose vs Standard-Dose Unfractionated Heparin for Percutaneous Coronary Intervention in Acute Coronary Syndromes Treated With Fondaparinux: The FUTURA/OASIS-8 Randomized Trial [Original Contribution]
Conclusion Low-dose compared with standard-dose unfractionated heparin did not reduce major peri-PCI bleeding and vascular access-site complications.
Trial Registration clinicaltrials.gov Identifier: NCT00790907 (Source: JAMA)...
POSTED 08/30/2010 at 01:48 PM --
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Elective Placement Of Type Of Pump Within The Aorta Prior To Percutaneous Coronary Intervention Not Associated With Improved Outcomes
High-risk patients undergoing a coronary procedure such as placement of a stent who electively received an intra-aortic balloon pump (a device that can help improve blood flow) prior to the procedure did not experience a significantly lower overall rate of events such as heart attack, revascularization or death, according to a study in the August 25 issue of JAMA... (Source: Health News from Medical News Today)...
POSTED 08/29/2010 at 03:00 AM --
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Same-day discharge âsafeâ for elective PCI patients
Same-day discharge of patients undergoing uncomplicated elective percutaneous coronary intervention is feasible, suggest US researchers. (Source: MedWire News - Cardiology)...
POSTED 08/28/2010 at 12:25 AM --
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AJC: Radial approach for PCI ups rad dose area
The transition from a default transfemoral access approach for coronary angioplasty to a default transradial approach increased fluoroscopy time, according to a study published in the September edition of American Journal of Cardiology. The transradial approach increased dose-area product for diagnostic procedures, but not interventional procedures. (Source: Cardiovascular Business News)...
POSTED 08/27/2010 at 08:32 AM --
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AJC: Radial approach for PCI ups rad dose area
The transition from a default transfemoral access approach for coronary angioplasty to a default transradial approach increased fluoroscopy time, according to a study published in the September edition of American Journal of Cardiology. The transradial approach increased dose-area product for diagnostic procedures, but not interventional procedures. (Source: Health Imaging News)...
POSTED 08/27/2010 at 08:32 AM --
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AJC: Radial approach for PCI ups rad dose area
The transition from a default transfemoral access approach for coronary angioplasty to a default transradial approach increased fluoroscopy time, according to a study published in the September edition of American Journal of Cardiology. The transradial approach increased dose-area product for diagnostic procedures, but not interventional procedures. (Source: Health Imaging News)...
POSTED 08/27/2010 at 08:32 AM --
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Significant Prostacyclin/Thromboxane Level Imbalance after Lower Limb Arterial Angioplasty: A Possible Platelet Function Alteration
Conclusions: PGI2/TX balance homeostasis is of significant pathophysiologic importance. The authors found that PTA results in significant PGI2/TX imbalance and shifts more toward increased TX production. This finding is partly suggestive of significant platelet activation. This imbalance in PGI2/TX level may have implications for future failure of PTA. Future research in reducing this platelet activation is recommended. (Source: Journal of Vascular and Interventional Radiology : JVIR)...
POSTED 08/27/2010 at 02:47 AM --
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Interventional Endovascular Management of Chronic Cerebrospinal Venous Insufficiency in Patients with Multiple Sclerosis: A Position Statement by the Society of Interventional Radiology, Endorsed by the Canadian Interventional Radiology Association
IT has been recently hypothesized that a phenomenon known as chronic cerebrospinal venous insufficiency (CCSVI) may play a significant role in the etiology, pathogenesis, and/or disease progression of multiple sclerosis (MS) (). Preliminary studies suggest that anatomical and physiological abnormalities of venous blood flow are significantly more common in patients with clinical MS than in healthy control subjects or patients with other neurologic disorders (). Of particular interest has been the documentation of stenotic and occlusive lesions in the azygos and internal jugular veins on duplex ultrasound and contrast venography of patients with clinical MS. One group () has reported improvement in clinical outcomes including quality of life in two small prospective uncontrolled cohorts of ......
POSTED 08/27/2010 at 02:47 AM --
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