Outcomes in Children After Intestinal Transplant
CONCLUSIONS:
Survival after intestinal transplant was associated with the underlying disease state. The explanation for these findings requires additional investigation into the differences in characteristics of the population of children with intestinal failure. (Source: PEDIATRICS)...
POSTED 03/01/2010 at 10:02 AM --
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Agricultural-related chemical exposures, season of conception, and risk of gastroschisis in Washington State
Objective: We sought to determine if periconceptional exposure to agrichemicals was associated with the development of gastroschisis.Study Design: We conducted a retrospective, case-controlled study using Washington State Birth Certificate and US Geological Survey databases. Cases included all live-born singleton infants with gastroschisis. Distance between a woman's residence and site of elevated exposure to agrichemicals was calculated. Multivariate regression was used to estimate the association between surface water concentrations of agrichemicals and the risk of gastroschisis.Results: Eight hundred five cases and 3616 control subjects were identified. Gastroschisis occurred more frequently among those who resided (Source: American Journal of Obstetrics and Gynecology)...
POSTED 02/28/2010 at 06:00 PM --
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Method to our madness: an 18-year retrospective analysis on gastroschisis closure
Conclusion: Although limited by retrospective biases, this study demonstrates that time to closure is the most significant variable related to LOS in gastroschisis. This relationship is intuitive since longer time to closure is probably determined by the severity of gastroschisis. The method of closure, by primary repair or silo, is of secondary importance. Conversely, unnecessarily increasing the time to closure may increase the LOS. The speed of reduction, whether through primary repair or by silo, should be guided by physiologic principles. (Source: Journal of Pediatric Surgery)...
POSTED 02/28/2010 at 06:00 PM --
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Serious birth defects linked to the agricultural chemical atrazine
(NaturalNews) Gastroschisis is a birth defect in which the intestines, and sometimes other organs, develop outside the fetal abdomen and poke out through an opening in the abdominal wall. Long considered a rare occurrence, gastroschisis has mysteriously been on the rise over the last three decades. In fact, the incidence of the defect has soared, increasing two to four times in the last 30 years. But why?Researchers think they've found the answer. The culprit behind the suffering of babies born with this condition appears to be the agricultural chemical atrazine. That's the conclusion of a study just presented at the annual meeting of the Society for Maternal-Fetal Medicine (SMFM) held in Chicago. Researchers at the University of Washington in Seattle were alerted to a higher than normal n......
POSTED 02/22/2010 at 01:00 AM --
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Weed Killer Atrazine May Be Linked to Gastroschisis
Living near farms that use the weed killer atrazine may up the risk of the rare birth defect gastroschisis, according to a study presented this past Friday at the annual meeting of the Society for Maternal-Fetal Medicine in Chicago. Reuters Health Information (Source: Medscape Ob/Gyn & Women's Health Headlines)...
POSTED 02/09/2010 at 11:52 AM --
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Link between birth defect gastroschisis and the agricultural chemical atrazine found
New findings demonstrate a link between the birth defect gastroschisis and the agricultural chemical atrazine. Gastroschisis is a type of inherited congenital abdominal wall defect in which the intestines, and sometimes other organs, develop outside the fetal abdomen through an opening in the abdominal wall. The incidence of gastroschisis is on the rise, increasing two to four times in the last 30 years. (Source: ScienceDaily Headlines)...
POSTED 02/07/2010 at 10:00 AM --
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Discovery Of Link Between Birth Defect Gastroschisis And The Agricultural Chemical Atrazine
In a study to be presented at the Society for Maternal-Fetal Medicine's (SMFM) annual meeting, The Pregnancy Meeting™ in Chicago, researchers unveiled findings that demonstrate a link between the birth defect gastroschisis and the agricultural chemical atrazine. Gastroschisis is a type of inherited congenital abdominal wall defect in which the intestines, and sometimes other organs, develop outside the fetal abdomen through an opening in the abdominal wall. The incidence of gastroschisis is on the rise, increasing two to four times in the last 30 years... (Source: Health News from Medical News Today)...
POSTED 02/05/2010 at 07:00 AM --
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Discovery Of Link Between Birth Defect Gastroschisis And The Agricultural Chemical Atrazine
In a study to be presented at the Society for Maternal-Fetal Medicine's (SMFM) annual meeting, The Pregnancy Meeting™ in Chicago, researchers unveiled findings that demonstrate a link between the birth defect gastroschisis and the agricultural chemical atrazine... (Source: GastroIntestinal News From Medical News Today)...
POSTED 02/05/2010 at 07:00 AM --
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Birth Defect Linked to Crop Chemical
Cases of gastroschisis, an abdominal wall birth defect, have risen two to four times in the last 30 years, and researchers have now linked it to the agricultural chemical atrazine. (Source: Medical Headlines From Ivanhoe.com)...
POSTED 02/04/2010 at 11:00 PM --
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A strategy for treatment of giant omphalocele.
CONCLUSION: The method we used can be performed at bedside and without the application of anesthesia, but should be tried on more patients to determine its effect.
PMID: 20119875 [PubMed - as supplied by publisher] (Source: World Journal of Pediatrics : WJP)...
POSTED 01/31/2010 at 06:00 PM --
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[Integrating the environmental clinic history into prenatal counseling and health care in gastroschisis: 2 case reports.]
CONCLUSIONS: 1. The PECH should be obtained in all patients with gastroschisis. 2. A thorough PECH requires a proper review of the related RFs and basic training to characterise and quantify environmental exposures. 3. Following these steps, useful recommendations to improve patient care and family advice in future pregnancies are provided.
PMID: 20122885 [PubMed - as supplied by publisher] (Source: Anales de Pediatria)...
POSTED 01/29/2010 at 06:00 PM --
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First-trimester sonographic findings in trisomy 18: a review of 53 cases
To report our experience with first-trimester sonographic findings in pregnancies complicated by trisomy 18.Proven cases of trisomy 18 undergoing sonographic examination between 11 + 0 and 13 + 6 weeks of gestation were retrospectively identified. Information on maternal demographics, prenatal sonographic findings, and chromosomal analysis results was obtained by reviewing the ultrasound reports and medical records.During the 12-year period from July 1997 to June 2009, 53 cases of full trisomy 18 had first-trimester sonographic examination performed at our institution. All but one fetus displayed one or more abnormal sonographic finding, most commonly increased nuchal translucency thickness (n = 48, 91%). Absent or hypoplastic nasal bone was documented in 53% of the fetuses in which this m......
POSTED 01/27/2010 at 06:00 PM --
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Inflammatory response in a rat model of gastroschisis is associated with an increase of NF-kappaB.
The objective of this study was to identify components of the inflammatory response in the intestine and liver in an experimental model of gastroschisis in rats. The model was surgically created at 18.5 days of gestation. The fetuses were exposed through a hysterotomy and an incision at the right of the umbilicus was made, exposing the fetal bowel. Then, the fetus was placed back into the uterus until term. The bowel in this model had macro- and microscopic characteristics similar to those observed in gastroschisis. The study was conducted on three groups of 20 fetuses each: gastroschisis, control, and sham fetuses. Fetal body, intestine and liver weights and intestine length were measured. IL-1beta, IL-6, IL-10, TNF-alpha, IFN-gamma and NF-kappaB levels were assessed by ELISA. Data were a......
POSTED 01/21/2010 at 06:00 PM --
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Association of Paternal Age and Risk for Major Congenital Anomalies From the National Birth Defects Prevention Study, 1997 to 2004
Conclusions: Our findings suggest that paternal age may be a risk factor for some multifactorial birth defects. (Source: Annals of Epidemiology)...
POSTED 01/06/2010 at 06:00 PM --
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Association of Paternal Age and Risk for Major Congenital Anomalies From the National Birth Defects Prevention Study, 1997 to 2004.
CONCLUSIONS: Our findings suggest that paternal age may be a risk factor for some multifactorial birth defects.
PMID: 20056435 [PubMed - as supplied by publisher] (Source: Annals of Epidemiology)...
POSTED 01/04/2010 at 06:00 PM --
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Aplasia cutis congenita associated with multiple congenital anomalies: case report.
DISCUSSION: Multiple factors have been described as etiological factors for ACC but the etiology is not clear yet. ACC may also be associated with some syndromes. Management strategies are based on the size, presence of an underlying skull defect and the child's physical condition.
PMID: 20066625 [PubMed - in process] (Source: Turkish Neurosurgery)...
POSTED 12/31/2009 at 06:00 PM --
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The prenatal or postnatal factors that predict complex gastroschisis in patients (atresia, volvulus, necrotic bowel and bowel perforation) remain controversial. The authors from Mott Children's Hospital in Ann Arbor evaluated the prognostic value of prenatal ultrasonographic parameters and early postnatal factors in predicting clinical outcomes. (Source: Journal of Pediatric Surgery)...
POSTED 12/31/2009 at 09:18 AM --
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Relationship between biopsy-proven parenteralnutrition-associated liver fibrosis and biochemical cholestasis in children with short bowel syndrome
Conclusions: In children with short bowel syndrome, biochemical cholestasis does not reflect the presence or degree of histologically confirmed PN-associated liver fibrosis. Careful follow-up, combined with further refinement of diagnostic and hepatoprotective strategies, may be warranted in this patient population. (Source: Journal of Pediatric Surgery)...
POSTED 12/31/2009 at 09:18 AM --
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In utero repair of gastroschisis in the sheep (Ovis aries) model
Conclusion: In utero anatomic repair of gastroschisis is possible in mid-gestation in the fetal lamb model, and it appears to ameliorate the inflammatory process. (Source: Journal of Pediatric Surgery)...
POSTED 12/31/2009 at 09:18 AM --
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Diagnosis and management of intestinal motility disorders
Gastrointestinal motility disorders in their most severe forms may directly lead to intestinal failure. Abnormal motor function may also contribute to the overall gut dysfunction of children who have other underlying gastrointestinal diseases, such as Hirschsprung disease or gastroschisis. Understanding the extent and the severity of the dysmotile segments has direct therapeutic and prognostic implications. Our ability to study gastrointestinal motility has greatly improved in the past few years, with the development of less-invasive diagnostic tests. Optimal treatment of children with intestinal motility disorders relies on a multidisciplinary approach, which focuses on optimizing nutrition, improving gastrointestinal motility, and reducing psychosocial disability. Patient education is im......
POSTED 12/31/2009 at 08:54 AM --
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