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Gallstones Medical and Health News Headlines
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All Recent Gallstones Medical Condition News Headlines |
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Long-term follow-up of patients with Bartter syndrome type I and II
Conclusions. Patients with Bartter syndrome type I and II tend to present a satisfactory prognosis after a median follow-up of more than 10 years. Gallstones might represent a new complication of antenatal Bartter syndrome. (Source: Nephrology Dialysis Transplantation)...
POSTED 08/24/2010 at 04:53 PM --

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Bleeding complications in laparoscopic cholecystectomy: Incidence, mechanisms, prevention and management
Conclusion: Good surgical technique, awareness and early recognition and management of such cases are keys to success when dealing with this problem. (Source: Journal of Minimal Access Surgery)...
POSTED 08/21/2010 at 03:15 AM --

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Feasibility of single-port laparoscopic cholecystectomy using a homemade laparoscopic port: a clinical report of 50 cases
Conclusion The homemade umbilical port reported in this study is useful for multiple instrument access and allows TUSPLC to be performed
safely, with its inherent cosmetic and cost advantages. Further studies of this technique are ongoing.
Content Type Journal ArticleDOI 10.1007/s00464-010-1287-4Authors
Kuo-Chang Wen, Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, TaiwanKai-Yuan Lin, Department of Medical Research, Chi-Mei Medical Center, Tainan, TaiwanYi Chen, Division of General Surgery, Department of Surgery, Chi-Mei Medical Center, Tainan, TaiwanYi-Feng Lin, Division of General Surgery, Department of Surgery, Chi-Mei Medical Center, Tainan, TaiwanKuo-Shan Wen, Department of Medical Research, Chi-Mei Medical Center, Tain......
POSTED 08/20/2010 at 12:47 AM --

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What Are Your Stomach Pain Symptoms Trying to Tell You?
If you are suffering from stomach pain, you need to find the cause before you can start a treatment. Here are a few of the conditions that can cause stomach pain.
Heartburn Related Resources:
Meal Planning Tips for Preventing Heartburn
Dining Out Without Heartburn
Foods with Little Risk of Causing Heartburn
Preventing Nighttime Heartburn
Peptic Ulcer Related Resources
Surgery for Peptic Ulcers
Complications of Peptic Ulcers
Peptic Ulcer Warning Signs
Peptic Ulcers in Children
Gallstone Related Resources:
What is the Gallbladder?
What are Gallstones?
What Increases the Risk of Developing Gallstones
Diagnosing Gallstones
What Are Your Stomach Pain Symptoms Trying to Tell You? originally appeared on About.com Heartburn / GERD on Monday, Au......
POSTED 08/08/2010 at 06:00 PM --

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Triglycerides and gallstone formation.
Authors: Smelt AH
Changes in bile acid (BA) metabolism and gallbladder function are critical factors in the pathogenesis of gallstones. Patients with hypertriglyceridemia (HTG) - often overweight and insulin resistant - are at risk for gallstone disease. The question arises whether HTG itself contributes to gallstone formation or whether gallstone disease only associate with this disorder. Triglycerides are formed in response to fluxes of non-esterified fatty acids and glucose. Hypertriglyceridemia results from either overproduction of triglycerides by the liver, impaired lipolysis or a combination of both. Hyperinsulinemia, as observed in the insulin resistant state, stimulates very low-density lipoprotein (VLDL)-triglyceride synthesis. Peroxisome proliferator-activated receptors (PPA......
POSTED 08/06/2010 at 06:00 PM --

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A mutation in PEX19 causes a severe clinical phenotype in a patient with peroxisomal biogenesis disorder
We report on a female infant, born to a consanguineous parents (first degree cousins), who presented with inactivity, poor sucking, and hypotonia early in the neonatal period. She had subtle dysmorphic features. Liver function tests were impaired with raised liver enzymes, conjugated and unconjugated hyperbilirubinemia. CT of the brain showed diffuse bilateral changes. She developed seizures with an abnormal EEG. Plasma very long chain fatty acid analysis showed high C26:0 levels and increasedC26:0/C22:0 and C24:0/C22:0 ratios, which is consistent with a PBD. Studies in fibroblasts including plasmalogen biosynthesis, peroxisomal fatty acid alfa and beta oxidation confirmed the diagnosis of PBD. Immunofluoresence microscopy revealed the absence of peroxisomes in fibroblasts. The patient was......
POSTED 08/02/2010 at 06:00 PM --

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The natural history of thalassemia intermedia
The severity of thalassemia intermedia depends on the degree of imbalance between alpha and non-alpha chains as well as other genetic and environmental factors that modify the natural history of the disease. By definition, the patients spontaneously maintain hemoglobin at or above 7 g/dL, sometimes at the price of intense hyperplasia of the bone marrow that is in turn responsible for bone deformities, osteoporosis, and extramedullary erythropoietic masses that often characterize thalassemia intermedia. Transfusion may become necessary with advancing age, during infection and pregnancy, and when hypersplenism develops. Splenectomy is often needed. Iron overload in nontransfused patients is due to increased gastrointestinal absorption and involves mainly the liver. Complications affecting th......
POSTED 08/01/2010 at 06:00 PM --

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Mucinous cystic neoplasms of the pancreas: how much preoperative evaluation is needed?
Authors: Theruvath TP, Morgan KA, Adams DB
Cystic lesions of the pancreas are identified with increasing frequency by modern imaging. The mucinous cystic neoplasm (MCN) is treated with resection for its malignant potential. How much preoperative evaluation is needed before undertaking operation is frequently a diagnostic dilemma. A retrospective review of 32 patients who underwent resection of a MCN between 1994 and 2007 was performed to define the preoperative evaluation and operative treatment of MCN patients. Thirty-two patients (30 women; mean age 49) had histology-proven MCN. Twenty-seven patients had symptomatic cysts (84%). Five had a history of gallstones and/or acute pancreatitis. All patients were worked up with CT and/or MRI. Endoscopic ultrasound was performed in 14 (44%) a......
POSTED 07/31/2010 at 06:00 PM --

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Laparoscopic versus open cholecystectomy in diabetic patients and postoperative outcome
Conclusions When feasible, LC was a safe procedure in diabetes. Open surgery with comorbidities increased the operative risks. Our study
was not randomized, and therefore selection bias to type of procedure may affect the results.
Content Type Journal ArticleDOI 10.1007/s00464-010-1248-yAuthors
Hannu Paajanen, Kuopio University Hospital Department of Surgery Kuopio FinlandSatu Suuronen, Mikkeli Central Hospital Department of Surgery Mikkeli FinlandPia Nordstrom, Mikkeli Central Hospital Department of Surgery Mikkeli FinlandPekka Miettinen, Kuopio University Hospital Department of Surgery Kuopio FinlandLeo Niskanen, Kuopio University Hospital Department of Medicine Kuopio Finland
Journal Surgical EndoscopyOnline ISSN 1432-2218Print ISSN 0930-2794 (Source: Surgi......
POSTED 07/27/2010 at 04:10 AM --

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Role of endoscopic ultrasound/SpyScope in diagnosis and treatment of choledocholithiasis in pregnancy.
We describe an alternative management strategy to conventional ERCP in a pregnant patient with choledocholithiasis and cholangitis detected using EUS and choledochoscopy.
PMID: 20653072 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)...
POSTED 07/26/2010 at 10:42 AM --

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An Unusual Complication Encountered Incidentally at Laparoscopic Cholecystectomy: A Case Series
Conclusion CBD erosion is a complication of plastic biliary stent insertion. CBD stent erosion will make surgery more hazardous especially
if it remains in situ for a significant period of time. CBD erosion can generally be managed conservatively without the need
for surgical repair. Awareness of this complication should prompt earlier surgery or earlier removal of plastic pigtail stents.
Content Type Journal ArticleCategory Case ReportDOI 10.1007/s11605-010-1238-3Authors
Mohammed Mohsin Uzzaman, North Middlesex University Hospital Department of General Surgery 62 Kensington Avenue London E12 6NP UKManojkumar S. Nair, North Middlesex University Hospital Department of General Surgery 62 Kensington Avenue London E12 6NP UKFiona Myint, North Middlesex University Hospit......
POSTED 07/23/2010 at 07:06 AM --

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Laparoscopic adjustable gastric banding (LAGB): surgical results and 5-year follow-up
Conclusions LAGB has low perioperative morbidity. However, its late complications are significant, and inadequate weight loss can be as
high as 46.3% after 5 years.
Content Type Journal ArticleDOI 10.1007/s00464-010-1176-xAuthors
Camilo Boza, Pontificia Universidad Católica de Chile Department of Digestive Surgery, Hospital ClÃnico Marcoleta 352 Santiago ChileCristian Gamboa, Pontificia Universidad Católica de Chile Department of Digestive Surgery, Hospital ClÃnico Marcoleta 352 Santiago ChileGustavo Perez, Pontificia Universidad Católica de Chile Department of Digestive Surgery, Hospital ClÃnico Marcoleta 352 Santiago ChileFernando Crovari, Pontificia Universidad Católica de Chile Department of Digestive Surgery, Hospital ClÃnico Marcoleta 352 Santiago ......
POSTED 07/23/2010 at 06:04 AM --

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Lack of adiponectin promotes formation of cholesterol gallstones in mice.
Authors: Ogiyama H, Kamada Y, Kiso S, Araki H, Yamada T, Nishihara T, Watabe K, Tochino Y, Kihara S, Funahashi T, Kanno K, Shimomura I, Tsutsui S, Tazuma S, Hayashi N
Plasma adiponectin levels are reduced in obese people, and hypoadiponectinemia is recently reported to associate with cholesterol gallstone formation in human. The aim of this study was to examine the role of adiponectin in gallstone formation using adiponectin knockout mice. We analyzed male knockout and C57BL6J mice fed normal or lithogenic diet for 6 weeks. On lithogenic diet, the prevalence rate of gallstone was significantly greater in knockout mice than C57BL6J mice. The molar percentages of beta and omega-muricholic acid were significantly higher and hepatic sterol 12alpha-hydroxylase expression (cyp8b1) was signif......
POSTED 07/22/2010 at 06:00 PM --

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Safety and effectiveness of outpatient laparoscopic cholecystectomy in a teaching hospital: a prospective study of 110 consecutive patients
Conclusions:
This study confirmed that OLC is clinical effective and can be performed safely in a teaching hospital by supervised HSTs. (Source: BMC Research Notes)...
POSTED 07/21/2010 at 06:00 PM --

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The fear of transgastric cholecystectomy: misinterpretation of the biliary anatomy
Conclusions Specific anatomic distortions due to NOTES technique together with the lack of exposure provided by current methods of retraction
tend to distort Calotâs triangle by flattening it rather than opening it out. At this stage, whenever the anatomy of the biliary
tract is unclear, a temporary âconversionâ to a laparoscopic view, more familiar to the surgeonâs eye, is recommended.
Content Type Journal ArticleCategory Multimedia ManuscriptDOI 10.1007/s00464-010-1234-4Authors
Silvana Perretta, University of Strasbourg IRCAD-EITS, Department of Gastrointestinal and Endocrine Surgery Strasbourg FranceBernard Dallemagne, University of Strasbourg IRCAD-EITS, Department of Gastrointestinal and Endocrine Surgery Strasbourg FranceGianfranco Donatelli, Universit......
POSTED 07/20/2010 at 02:53 AM --

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Hepatic Haemangioma Masquerading as the Gallbladder in a Case of Gallbladder Agenesis: A Case Report and Literature Review
We describe the first documented case of gallbladder agenesis where the clinical presentation was consistent with biliary colic, and radiological investigation suggested the presence of gallstones. Subsequent operative findings revealed a solitary haemangioma of the liver sited in the normal position of the gallbladder fossa but with absence of the gallbladder. It is important that clinicians should keep gallbladder agenesis in mind when the gallbladder appears abnormal on preoperative imaging studies and cannot be found at laparoscopy. As symptoms will improve in 98% of cases, it is very important to avoid unnecessary intervention in patients who have a negative laparoscopy. The clinical presentation, investigations, and operative findings are discussed with a review of other relevant rep......
POSTED 07/20/2010 at 02:03 AM --

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Me and my operation: How 3D glasses tackled my gall stones
Stephen Kean, 38, has just become the first person in the world to have keyhole surgery using 'Avatar'-style 3D technology to tackle gallstones. (Source: the Mail online | Health)...
POSTED 07/12/2010 at 08:05 PM --

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Hydrophobic bile salts inhibit gallbladder smooth muscle function via stimulation of GPBAR1 receptors and activation of KATP channels.
Authors: Lavoie B, Balemba OB, Godfrey C, Watson CA, Vassilleva G, Corvera CU, Nelson MT, Mawe GM
Hydrophobic bile salts are thought to contribute to the disruption of gallbladder smooth muscle (GBSM) function that occurs in gallstone disease, but their mechanism of action is unknown. The current study was undertaken to determine how hydrophobic bile salts interact with GBSM, and how they reduce GBSM activity. The effect of hydrophobic bile salts on the activity of GBSM was measured by intracellular recording and calcium imaging using wholemount preparations from guinea pig and mouse gallbladder. RT-PCR and immunohistochemistry were used to evaluate expression of the G-protein coupled bile acid receptor, GPBAR1. Application of tauro-chenodeoxycholate (CDC, 50-100 muM) to in situ GBSM r......
POSTED 07/11/2010 at 06:00 PM --

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Metabolic profiling of bile in cholangiocarcinoma using in vitro magnetic resonance spectroscopy
Conclusions: These preliminary data suggest that altered bile acid and PtC metabolism play an important role in CCA aetiopathogenesis and that specific metabolites may have potential as future biomarkers. (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)...
POSTED 07/10/2010 at 06:00 PM --

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Overcoming the difficulties in laparoscopic management of contracted gallbladders with gallstones: possible role of fundus-down approach
Conclusions It appears that fundus-down laparoscopic cholecystectomy is associated with lower conversion and complication rates and shorter
postoperative hospital stay as compared with conventional laparoscopic cholecystectomy when used to treat patients with contracted
gallbladders and gallstones.
Content Type Journal ArticleDOI 10.1007/s00464-010-1175-yAuthors
Shing-Moo Huang, Chung Shan Medical University Institute and School of Medicine Taichung Taiwan, Republic of ChinaKuang-Ming Hsiao, National Chung Cheng University Department of Life Science Minhsiung Chia-Yi Taiwan, Republic of ChinaHuichin Pan, Chung Shan Medical University Hospital Department of Medical Research Taichung Taiwan, Republic of ChinaChung-Chin Yao, Chung Shan Medical University Institute and ......
POSTED 07/10/2010 at 02:02 AM --

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