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Congestive Heart Failure Medical and Health News Headlines
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All Recent Congestive Heart Failure Medical Condition News Headlines |
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Bioheart Launches First US FDA Approved Clinical Trial That Tests Gene-Modified Stem Cell Therapy In Patients With Congestive Heart Failure
Bioheart, Inc., (OTCBB:BHRT) announced that the company has commenced work on its REGEN trial, a Phase I Clinical Trial to test genetically modified MyoCell® in patients suffering from Congestive Heart Failure (CHF). Bioheart's MyoCell® is a regenerative cell therapy that uses myoblasts, or muscle stem cells,that are grown from a patient's own muscle... (Source: Cardiovascular / Cardiology News From Medical News Today)...
POSTED 02/07/2010 at 02:00 AM --
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Applicability of Body Surface Potential Map in Computerized Optimization of Biventricular Pacing.
Authors: Miri R, Graf IM, Bayarri JV, Dössel O
Biventricular pacing (BVP) could be improved by identifying the patient-specific optimal electrode positions. Body surface potential map (BSPM) is a non-invasive technique for obtaining the electrophysiology and pathology of a patient. The study proposes the use of BSPM as input for an automated non-invasive strategy based on a personalized computer model of the heart, to identify the patient pathology and specific optimal treatment with BVP devices. The anatomy of a patient suffering from left bundle branch block and myocardial infarction is extracted from a series of MR data sets. The clinical measurements of BSPM are used to parameterize the computer model of the heart to represent the individual pathology. Cardiac electrophysiolog......
POSTED 02/04/2010 at 06:00 PM --
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Bioheart Launches First US FDA Approved Clinical Trial that Tests Gene-Modified Stem Cell Therapy in Patients with Congestive Heart Failure
SUNRISE, Fla.--(HSMN NewsFeed)--Bioheart, Inc., (OTCBB:BHRT ) announced today that the company has commenced work on its REGEN trial, a Phase I Clinical Trial to test genetically modified MyoCell® in patients suffering from Congestive Heart Failure (CH... Regenerative Medicine, CardiologyBioheart, MyoCell, REGEN trial, stem cell (Source: HSMN NewsFeed)...
POSTED 02/04/2010 at 03:47 PM --
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Kinked Carotids
An 80-year-old woman presented with congestive heart failure due to aortic insufficiency associated with a markedly dilated ascending aorta. On physical examination, she was noted to have a pulsatile mass ... (Source: New England Journal of Medicine)...
POSTED 02/02/2010 at 06:00 PM --
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Vein of Galen arteriovenous malformation with PAPVR and use of serial B-type natriuretic peptide levels in the management: a case report and review of the literature
Conclusions:
Rapid diagnosis and treatment in infants with complex conditions such as this are imperative to expedite appropriate treatments, preventing long term negative outcome. (Source: BioMed Central)...
POSTED 02/01/2010 at 06:00 PM --
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Prognostic implications of left ventricular dyssynchrony early after non-ST elevation myocardial infarction without congestive heart failure
Conclusion
After NSTEMI, proximal LCx stenosis and impaired LV function independently predicted LV dyssynchrony. The composite dyssynchrony score had prognostic value and identified patients with persistently dilated and impaired LV on follow-up. (Source: European Heart Journal)...
POSTED 02/01/2010 at 02:06 AM --
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Cheyne–Stokes respiration in heart failure: Cycle length is dependent on left ventricular ejection fraction
Abstract: Background: Cheyne–Stokes respiration (CSR) is common in patients with congestive heart failure (CHF) and is associated with poor prognosis. The aim of this study was to analyse the characteristics of CSR in patients with varying degrees of impaired left ventricular ejection fraction (LVEF).Methods: A total of 104 patients with CSR (apnea–hypopnea index [AHI]⩾15/h) and exertional dyspnea were divided into FIVE groups according to their LVEF (50%) and the worst LVEF ( (Source: Sleep Medicine)...
POSTED 01/31/2010 at 06:00 PM --
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Does aspirin use adversely influence intermediate-term postdischarge outcomes for hospitalized patients who are treated with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers? Findings from Organized Program to Facilitate Life-Saving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF)
Conclusions: When combined with ACEI or ARB, ASA had no demonstrable adverse effect on intermediate-term postdischarge outcomes for patients with ischemic or nonischemic HF. (Source: American Heart Journal)...
POSTED 01/31/2010 at 06:00 PM --
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Influence of dedicated heart failure clinics on delivery of recommended therapies in outpatient cardiology practices: Findings from the Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting (IMPROVE HF)
Conclusions: Use of dedicated HF clinics varied in cardiology outpatient practices and was associated with greater use of cardiac resynchronization therapy and HF education but not other guideline-recommended therapies. (Source: American Heart Journal)...
POSTED 01/31/2010 at 06:00 PM --
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Systematic review of trials using vasodilators in pulmonary arterial hypertension: Why a new approach is needed
Conclusions: The impact of vasodilators on long-term survival in pulmonary arterial hypertension remains uncertain. Future trials need to (a) adopt new trial designs that can better address clinical benefits, (b) use new end points that incorporate our best understanding of the disease rather than the ones that are easy to administer, and (c) include longer durations of study and other strategies to clarify if survival is affected. (Source: American Heart Journal)...
POSTED 01/31/2010 at 06:00 PM --
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New pharmacotherapy for stroke prevention in atrial fibrillation: Update 2010.
Authors: Armaganijan L, Eikelboom J, Healey JS, Morillo CA
Atrial fibrillation (AF) is the most commonly encountered arrhythmia in clinical practice and is associated with substantial morbidity and mortality. Its prevalence increases with age, affecting about 1% of patients aged <60 years and almost 10% of patients >80 years. AF is associated with a fivefold increasing risk of embolism or stroke with absolute risk ranging from less than 1% to 20% per year, depending on patient age and the presence of clinical risk factors including congestive heart failure, systemic hypertension, diabetes mellitus and prior history of cardioembolic events. Vitamin K antagonists (VKAs) and acetyl salicylic acid are currently the only licensed antithrombotic therapies for stroke prevention in patie......
POSTED 01/31/2010 at 06:00 PM --
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Partial mechanical long-term support with the CircuLite Synergy pump as bridge-to-transplant in congestive heart failure.
CONCLUSIONS: The CircuLite Synergy device is a partial support pump, which is easy to implant and which provides hemodynamic benefits in bridging heart failure patients to cardiac transplant.
PMID: 20101535 [PubMed - in process] (Source: The Thoracic and Cardiovascular Surgeon)...
POSTED 01/31/2010 at 06:00 PM --
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Inhibition of mitochondrial translocator protein prevents atrial fibrillation.
Authors: Li J, Xiao J, Liang D, Zhang H, Zhang G, Liu Y, Zhang Y, Liu Y, Yu Z, Yan B, Jiang B, Li F, Peng L, Zhou ZN, Chen YH
Atrial fibrillation is the most common arrhythmia encountered in clinical practice. It can cause severe complications such as congestive heart failure and stroke. However, identification of prime targets for efficient therapeutic intervention remains a challenge. In vitro rabbit heart models of ischemia-, stretch-, and cholinergic agitation-induced atrial fibrillation were developed, and pharmacological interventions of mitochondrial translocator protein (TSPO) were adopted to explore the role of the mitochondrial protein in the aforementioned atrial fibrillations. Fura-2 AM and Mg(2+)-Fura-2 AM were used to monitor the alterations of intracellular Ca(2+) and AT......
POSTED 01/29/2010 at 06:00 PM --
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Surgery helps chronic sinusitis sufferers get relief
Up to 76 percent of patients with chronic rhionsinusitis reported improved quality of life following endoscopic surgery. Prior to surgery, adults with chronic rhinosinusitis typically have lower quality of life scores than patients with congestive heart failure, angina, chronic obstructive pulmonary disease or back pain. (Source: ScienceDaily Headlines)...
POSTED 01/28/2010 at 04:00 PM --
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Carvedilol may alleviate late cardiac remodelling following surgical ventricular restoration [Original articles]
Conclusions: High-dose carvedilol alleviated LV remodelling and diastolic dysfunction following SVR accompanying with reduction in myocardial fibrosis. Blockade of β-adrenergic receptor may be a promising adjuvant therapy in patients following SVR. (Source: European Journal of Cardio-Thoracic Surgery)...
POSTED 01/28/2010 at 01:40 PM --
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Early changes in contractility indices and fibrosis in two minimally invasive congestive heart failure models [Original articles]
Conclusions: The two heart failure models we describe were relatively simple to create and maintain, minimally invasive, accurate, inexpensive and, importantly, had a low mortality rate. These models rapidly induced deterioration of contractility indices and onset of fibrosis, the hallmarks of early myocardial dysfunction associated with heart failure. Sonomicrometry assessments were able to detect early contractility changes prior to clinical signs. (Source: European Journal of Cardio-Thoracic Surgery)...
POSTED 01/28/2010 at 01:40 PM --
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Early recovery of left ventricle following coronary artery bypass grafting and mitral valve repair in a case of anomalous origin of left coronary artery from pulmonary artery
We report a critically ill infant with ALCAPA
needing myocardial revascularization and MV repair after which there was early recovery of Left Ventricular (LV) function.
At two years follow up, the child is clinically well; the postoperative cardiac catheterization shows good flow in the Left
Internal Mammary Artery (LIMA) and Left Anterior Descending artery (LAD), good LV function and competent mitral valve.
Content Type Journal ArticleCategory Case ReportsDOI 10.1007/s12055-009-0046-4Authors
Raj Gopal Menon, The Sultanate of Oman Department of Cardiothoracic Surgery Oman Saudi ArabiaSalim Maskari, The Sultanate of Oman Department of Cardiothoracic Surgery Oman Saudi ArabiaJohn Valliattu, The Sultanate of Oman Department of Cardiothoracic Surgery Oman Saudi ArabiaTaha Al Delamie, T......
POSTED 01/27/2010 at 02:49 PM --
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Current Expectations for Surgical Repair of Isolated Ventricular Septal Defects [ORIGINAL ARTICLES: PEDIATRIC CARDIAC]
Conclusions
Surgical closure of isolated VSD is a safe, effective therapy. Risk of death, complete heart block, and reoperation is minimal. As new technologies for VSD closure evolve, results such as these should be considered when evaluating patients, choosing therapeutic options, and counseling families. (Source: The Annals of Thoracic Surgery)...
POSTED 01/27/2010 at 01:27 PM --
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Surgery helps chronic sinusitis sufferers get relief
(Oregon Health & Science University) A new study led by Oregon Health & Science University shows up to 76 percent of patients with chronic rhionsinusitis reported improved quality of life following endoscopic surgery. Prior to surgery, adults with chronic rhinosinusitis typically have lower quality of life scores than patients with congestive heart failure, angina, chronic obstructive pulmonary disease or back pain. (Source: EurekAlert! - Medicine and Health)...
POSTED 01/26/2010 at 11:00 PM --
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An 86-Year-Old Woman With Cardiac Cachexia Contemplating the End of Her Life: Review of Hospice Care [Clinical Crossroads]
Mrs H is an 86-year-old woman with progressive congestive heart failure and multiple chronic conditions who is experiencing worsening function and quality of life despite maximum medical therapies. She seeks advice regarding control over the circumstances of the end of her life, be it by suicide or under hospice care. Typical of US populations older than 65 years with multiple chronic health conditions and functional decline who are facing the end of life, Mrs H's concerns are particularly about quality of life, not being a burden on loved ones, and maintaining control. As she demonstrates, psychological, existential, and social factors, particularly fear of being a burden, are more common reasons for desiring hastened death than those related directly to physical symptoms. Hospice, which ......
POSTED 01/26/2010 at 03:07 PM --
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