The normal and abnormal owl monkey (Aotus sp.) heart: looking at cardiomyopathy changes with echocardiography and electrocardiography
Conclusions Aged Aotus had increased left ventricular posterior wall thickness over young animals. Left ventricular diameter and ejection fraction appeared to be the best identifying measurements for cardiomyopathy. There were no differences in the ECG. (Source: Journal of Medical Primatology)...
POSTED 02/07/2010 at 06:00 PM --
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Echocardiography of the Right Ventricle in Athlete's Heart and Hearts of Normal Size Compared to Magnetic Resonance Imaging: Which Measurements Should be Applied in Athletes?
In conclusion, two-dimensional echocardiographic RV measurements offer only a limited potential to reflect true RV dimensions. Only RV-EDD may differentiate between normal hearts and exercise related RV adaptations in AH, and is the only recommendable parameter to be measured in athletes routinely. In unclear cases additional methods should be used to examine the RV in athletes.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents | Abstract | Full text (Source: International Journal of Sports Medicine)...
POSTED 02/05/2010 at 09:44 AM --
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Usefulness of Cardiac Resynchronization Therapy in Patients With Adriamycin-Induced Cardiomyopathy
In conclusion, patients with AIC may derive a significant echocardiographic and symptomatic benefit from CRT, which is similar to that seen in other forms of NIC. (Source: The American Journal of Cardiology)...
POSTED 02/05/2010 at 07:55 AM --
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Morphologic Features of Exertional Versus Nonexertional Sudden Death in Patients With Hypertrophic Cardiomyopathy
In conclusion, there are no pathologic features that would identify patients with HC at risk for exertional death. Because relatively decreased heart weight is strongly associated with exertional death, and because a large proportion of exertional deaths with HC are not associated with significant asymmetry, cardiologists should be careful in excluding the diagnosis of HC in athletes with even mild degrees of cardiomegaly, especially young men. (Source: The American Journal of Cardiology)...
POSTED 02/05/2010 at 07:55 AM --
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De novo triple segmental aneuploid of 1p, 1q, and 4q in a girl with hypertrophic cardiomyopathy, muscle hypotonia, and multiple congenital anomalies
(Source: American Journal of Medical Genetics Part A)...
POSTED 02/04/2010 at 06:00 PM --
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Takotsubo Cardiomyopathy as an Underlying Mediator of Myocardial Infarction with Normal Coronary Arteries
Cardiology 2010;115:186190 (DOI:10.1159/000280810) (Source: Karger Publishers)...
POSTED 02/04/2010 at 05:00 PM --
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Authors' response
(Source: Heart)...
POSTED 02/04/2010 at 09:44 AM --
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Reply
We appreciate the correspondence from Dr. Murgo, stimulated by our recent historical review focused on the evolving understanding of left ventricular (LV) outflow gradients in hypertrophic cardiomyopathy (HCM) (). Dr. Murgo has had an important role in this conversation, which has spanned virtually the last 5 decades (), for this heterogeneous disease with complex ejection dynamics (). (Source: Journal of the American College of Cardiology)...
POSTED 02/04/2010 at 07:51 AM --
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Compound and Digenic Heterozygosity Contributes to Arrhythmogenic Right Ventricular Cardiomyopathy
Conclusions: These data suggest that the genetic basis of ARVC includes reduced penetrance with compound and digenic heterozygosity. Disturbed junctional cytoarchitecture in subjects with desmosomal mutations confirms that ARVC is a disease of the desmosome and cell junction. (Source: Journal of the American College of Cardiology)...
POSTED 02/04/2010 at 07:51 AM --
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Significance of Maximal and Regional Left Ventricular Wall Thickness in Association With Arrhythmic Events in Patients With Hypertrophic Cardiomyopathy.
Conclusions: Non-invasive imaging measures, such as LVWT, do have a role in identifying the patients at risk of VAEs. In addition to maximal LVWT, the key regional LVWTs provide complementary information of incremental value to the conventional risk stratification model.
PMID: 20134097 [PubMed - as supplied by publisher] (Source: Circulation Journal)...
POSTED 02/03/2010 at 06:00 PM --
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Impaired Cardiovascular Function in Primary Biliary Cirrhosis.
Conclusion: Our findings suggest the presence of altered myocardial function in PBC. Autonomic "dysfunction" may, rather than being an abnormal process, represent a compensatory mechanism to increase cardiac return to mitigate these effects.
PMID: 20133949 [PubMed - as supplied by publisher] (Source: Am J Physiol Gastroi...)...
POSTED 02/03/2010 at 06:00 PM --
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Are Electrocardiographic Changes in Patients with Acute Subarachnoid Hemorrhage Associated with Takotsubo Cardiomyopathy?
Cardiology 2010;115:182183 (DOI:10.1159/000280396) (Source: Karger Publishers)...
POSTED 02/03/2010 at 05:00 PM --
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Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging
In conclusion, conditional expression of I-1c or I-1S67A enhanced steady-state phosphorylation of 2 key Ca2+-regulating sarcoplasmic reticulum enzymes. This was associated with increased contractile function in young animals but also with arrhythmias and cardiomyopathy after adrenergic stress and with aging. These data should be considered in the development of novel therapies for heart failure. (Source: Journal of Clinical Investigation)...
POSTED 02/02/2010 at 10:14 AM --
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Stomach Pierced by Apical Cuff late after Removal of Toyobo Assist Device [CASE STUDIES]
A 38-year-old woman suffering from dilated cardiomyopathy underwent successful removal of a Toyobo left ventricular assist device after 11 months of support. Four months later, discharge of pus from the skin resulted from the contaminated residual apical cuff. The purulence stopped spontaneously 16 months later, but halitosis then developed. Two weeks later, fever and hematemesis occurred. Emergency surgery revealed gastric perforation by the apical cuff, which was removed under cardiopulmonary bypass. (Source: Asian Cardiovascular and Thoracic Annals)...
POSTED 02/02/2010 at 03:27 AM --
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Takotsubo Cardiomyopathy, or Broken-Heart Syndrome (March).
CONCLUSIONS: Takotsubo cardiomyopathy causes a reversible left ventricle dysfunction which occurs most commonly in postmenopausal women with or without cardiovascular disease. Recognition is detected with coronary angiography. It is thought to primarily be due to an abnormally high sympathetic stimulation after emotional or psychological stress. Treatment consists of an angiotensin converting enzyme inhibitor and/or beta blocker if needed for left ventricular dysfunction and possibly an anxiolytic agent.
PMID: 20124462 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy)...
POSTED 02/01/2010 at 06:00 PM --
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Clinical practice
Abstract The current maintenance treatment for children with heart failure remains controversial: To a large extent, it is based on
extrapolation of data derived from trials in adult populations. There are only a few randomized trials focused on the treatment
of children with cardiac disease, especially in the subgroup with cardiomyopathy and heart failure. The goals of therapy are
to maintain circulatory and end-organ function and to allow for recovery and reverse remodeling to occur. When maintenance
therapy fails and medical treatment does not result in clinical improvement, the alternative of device therapy must be considered:
In that case, the usual aim is to stabilize circulatory status, as a bridge to either recovery or to cardiac transplantation.
Recently, carefull......
POSTED 02/01/2010 at 12:02 PM --
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Clinical Approach to Sudden Cardiac Death Syndromes
Clinical cardiologists are encountering an important challenge in the care of families with inherited cardiac diseases. The majority of the inherited cardiac diseases causing sudden death express themselves at variable ages in the form of altered muscle function – for instance hypertrophic or dilated cardiomyopathy – or in the form of arrhythmias, including Brugada syndrome and long QT ... (Source: Springer Medicine titles)...
POSTED 02/01/2010 at 10:06 AM --
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Right ventricular hypertrophy and scarring in mutation positive hypertrophic cardiomyopathy
(Source: European Heart Journal)...
POSTED 02/01/2010 at 02:06 AM --
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Atrial fibrillation and long-term prognosis in patients hospitalized for heart failure: results from heart failure survey in Israel (HFSIS)
Conclusion
AF was present in a third of hospitalized HF patients, and identified a population with increased mortality risk, largely due to co-morbidities. (Source: European Heart Journal)...
POSTED 02/01/2010 at 02:06 AM --
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The role of oestrogen in the pathophysiologic process of the Tako-Tsubo cardiomyopathy
(Source: European Heart Journal)...
POSTED 02/01/2010 at 02:06 AM --
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