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Bronchitis Medical and Health News Headlines
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All Recent Bronchitis Medical Condition News Headlines |
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[Annual review of archives in interventional pneumology, interstitial diseases and lung transplantation]
Authors: Disdier C, Bollo E, Morales P, Montero C
A review has been made of original articles on invasive pneumology techniques, interstitial diseases and lung transplantation, published in the Archivos de Bronconeumología during the year 2008. We have selected the publication by Martínez-Olondrins et al on the mediastinal staging of bronchogenic carcinoma by <<blind>> transbronchial needle aspiration to highlight the role of this simple, safe and cost-effective technique at a time when aspiration by ultrasound-guided bronchoscopy is profiled as an alternative to staging by mediastinoscopy. Besides its usefulness in the study of lymph nodes, transbronchial needle aspiration increases the overall performance of bronchoscopy by 20%, which means that it should be con......
POSTED 06/27/2009 at 05:30 AM --
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Respiratory viral infections detected by multiplex PCR among pediatric patients with lower respiratory tract infections seen at an urban hospital in Delhi from 2005 to 2007
Conclusions:
Multiplex PCR offers a rapid, sensitive and reasonably priced diagnostic method for common respiratory viruses. (Source: Virology Journal)...
POSTED 06/25/2009 at 06:00 PM --
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Bronchiolitis: Age and Previous Wheezing Episodes Are Linked to Viral Etiology and Atopic Characteristics
In children with bronchiolitis, 2 clinical factors, age and number of previous wheezing episodes, are linked to inflammatory and virologic risk factors of asthma. The Pediatric Infectious Disease Journal® (Source: Medscape Allergy Headlines)...
POSTED 06/24/2009 at 12:46 PM --
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Aspergillus Colonization of the Lung Allograft Is a Risk Factor for Bronchiolitis Obliterans Syndrome
Weigt SS, Elashoff RM, Huang C, Ardehali A, Gregson AL, Kubak B, Fishbein MC, Saggar R, Keane MP, Saggar R, Lynch Iii JP, Zisman DA, Ross DJ, Belperio JA (Source: The Aspergillus Website - articles)...
POSTED 06/22/2009 at 06:00 PM --
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[Archimedes] QUESTION 1
(Source: Archives of Disease in Childhood)...
POSTED 06/18/2009 at 06:00 PM --
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Lung function, sociodemographic characteristics, and psychological reaction to transplant associated with chronic stress among lung recipients.
In this study, we investigated whether physical, sociodemographic, or transplant-related psychological factors were associated with the patient's chronic stress level. A cross-sectional study enrolling 76 patients measured chronic stress (Screening Scale, Screening Subscale of Chronic Stress of the Trier Inventory for the Assessment of Chronic Stress) and the emotional effects of the transplant (Transplant Effects Questionnaire), as well as physical and sociodemographic conditions (lung function, bronchiolitis obliterans syndrome, working status, and parenting). Chronic stress after a lung transplant was significantly lower than in a normal community sample. In the multiple regression analysis, worries concerning the transplant were significantly associated with the patient's chronic stres......
POSTED 06/17/2009 at 06:00 PM --
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Photopheresis therapy for problematic renal allograft rejection
Conclusion: Photopheresis may have a role as an adjuvant or salvage antirejection therapy in solid organ transplantation. Furthermore, evaluation in randomized controlled clinical trials is required to evaluate its potential. J. Clin. Apheresis, 2009. © 2009 Wiley-Liss, Inc. (Source: Journal of Clinical Apheresis)...
POSTED 06/16/2009 at 06:00 PM --
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An Unwelcome Guest: Aspergillus Colonization in Lung Transplantation and Its Association with Bronchiolitis Obliterans Syndrome
(Source: American Journal of Transplantation)...
POSTED 06/15/2009 at 06:00 PM --
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Immunobiology of Chronic Lung Allograft Dysfunction: New Insights from the Bench and Beyond
The first successful human lung transplants were performed in the 1980s. Since that time lung transplantation has been a therapeutic modality for end-stage pulmonary diseases. However, chronic rejection, known as obliterative bronchiolitis (OB)/bronchiolitis obliterans syndrome (BOS), is the key reason why the 5-year survival is only 50%, which is significantly worse than most other solid organ transplants. Recent studies have provided exciting advances that are beginning to be translated into findings in humans. This review will highlight the current advances in understanding the mechanisms of OB/BOS in lung transplant recipients. (Source: American Journal of Transplantation)...
POSTED 06/09/2009 at 06:00 PM --
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Medium-term outcome of fundoplication after lung transplantation
Gastroesophageal reflux disease (GERD) in lung transplant recipients has gained increasing attention as a factor in allograft failure. There are few data on the impact of fundoplication on survival or lung function, and less on its effect on symptoms or quality of life. Patients undergoing fundoplication following lung transplantation from 1999 to 2005 were included in the study. Patient satisfaction, changes in GERD symptoms, and the presence of known side effects were assessed. The effect on lung function, body mass index, and rate of progression to the bronchiolitis obliterans syndrome (BOS) were recorded. Twenty-one patients (13 males), in whom reflux was confirmed on objective criteria, were included, with a mean age of 43 years (range 20[ndash]68). Time between transplantation and fu......
POSTED 06/08/2009 at 11:00 PM --
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PARI Pharma Reports Successful Phase Ib Clinical Results for Inhaled Liposomal Cyclosporine A and Gains FDA Orphan Drug Designation for the Prevention and Treatment of Bronchiolitis Obliterans
MONTEREY, Calif., June 02, 2009 /PRNewswire/ -- This month's Journal of Aerosol Medicine and Pulmonary Drug Delivery features positive Phase Ib clinical trial results for PARI Pharma's L-CsA, inhaled liposomal cyclosporine A. In May, PARI Pharma... (Source: Drugs.com - Clinical Trials)...
POSTED 06/05/2009 at 08:25 AM --
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Recent Developments in Heliox Therapy for Asthma and Bronchiolitis
This article will primarily focus on heliox inhalation therapy and heliox-driven nebulizer therapy for acute asthma exacerbations. The emergence of heliox inhalation therapy for acute viral bronchiolitis will also be addressed. (Source: Clinical Pediatric Emergency Medicine)...
POSTED 05/31/2009 at 11:00 PM --
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Critically ill infants benefit from early administration of protein and energy-enriched formula: A randomized controlled trial
Summary: Background & aims: Nutritional support improves outcome in critically ill infants but is impeded by fluid restriction, gastric intolerance and feeding interruptions. Protein and energy-enriched infant formulas may help to achieve nutritional targets earlier during admission and promote anabolism.Methods: Randomized controlled design. Infants with respiratory failure due to RSV-bronchiolitis received a protein and energy-enriched formula (PE-formula, n=8) or a standard formula (S-formula, n=10) during 5 days after admission. Primary outcome: nutrient delivery, energy and nitrogen balance and plasma amino acid concentrations. Secondary outcome: tolerance and safety.Results: Nutrient intakes were higher in PE fed infants and met population reference intake (PRI) on day 3–5 whilst i......
POSTED 05/31/2009 at 11:00 PM --
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Bronchiolitis Burden Reduced by Combo Tx
The combination of oral dexamethasone and nebulized epinephrine appeared to reduce hospital admission, hasten discharge from the emergency department, and decrease the duration of symptoms in infants with bronchiolitis. (Source: Pediatric News)...
POSTED 05/31/2009 at 06:00 PM --
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Efficacy of Total Lymphoid Irradiation in Azithromycin Nonresponsive Chronic Allograft Rejection After Lung Transplantation
Abstract: Bronchiolitis obliterans syndrome (BOS) remains a major problem after lung transplantation. Azithromycin seems to be beneficial in some patients with established BOS. We investigated the efficacy of total lymphoid irradiation (TLI) in 6 BOS patients with a continuous decline in FEV1, despite treatment with azithromycin for a mean of 12 ± 13 (range, 1–35) months. A historical control group consisted of 5 patients with declining FEV1, also nonresponders to azithromycin and those not treated with TLI. All 6 TLI patients received the total dose of 8 Gy in 10 sessions. There was a significant change in the decline of the FEV1 after TLI treatment (from 221 ± 107 to 94 ± 79 mL/mo; P = .041). Three patients died, due to BOS progression, overwhelming pneumonia, and sudden cardiac arr......
POSTED 05/31/2009 at 06:00 PM --
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Tacrolimus Versus Cyclosporine for Adult Lung Transplant Recipients: A Meta-Analysis
Conclusion: Using tacrolimus as primary immunosuppressant for lung transplant recipient resulted in comparable survival and reduction in acute rejection episodes when compared with cyclosporine. (Source: Transplantation Proceedings)...
POSTED 05/31/2009 at 06:00 PM --
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[Case report] Granulomatous bronchiolitis of Crohn's disease successfully treated with inhaled budesonide
A 39-year-old white woman with longstanding Crohn’s disease presented with the rare complication of granulomatous bronchiolitis. Rapid resolution after inhaled budesonide is highlighted, as this is the first case described in the literature successfully treated without the need for systemic therapy. This less toxic approach to therapy is warranted in granulomatous bronchiolitis of Crohn’s disease to avoid unwanted side effects of steroids and infliximab. (Source: Thorax)...
POSTED 05/27/2009 at 11:00 PM --
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Local C-Reactive Protein Expression in Obliterative Lesions and the Bronchial Wall in Posttransplant Obliterative Bronchiolitis
The local immunoreactivity of C-reactive protein (CRP) was studied in a heterotopic porcine model of posttranplant obliterative bronchiolitis (OB). Bronchial allografts and control autografts were examined serially 2–28 days after subcutaneous transplantation. The autografts stayed patent. In the allografts, proliferation of inflammatory cells (P<.0001) and fibroblasts (P=.02) resulted in occlusion of the bronchial lumens (P<.01). Influx of CD4+ (P<.001) and CD8+ (P<.0001) cells demonstrated allograft immune response. CRP positivity simultaneously increased in the bronchial walls (P<.01), in macrophages, myofibroblasts, and endothelial cells. Local CRP was predictive of features characteristic of OB (R=0.456–0.879, P< .05−P......
POSTED 05/27/2009 at 01:37 AM --
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Targeting Allograft Injury and Inflammation in the Management of Post-Lung Transplant Bronchiolitis Obliterans Syndrome
Chronic allograft dysfunction, manifesting as bronchiolitis obliterans syndrome (BOS), is the major cause of morbidity and mortality in human lung transplant recipients. While alloimmunity has a definite role, there is increasing interest in overall allograft injury and subsequent inflammation and remodeling. This review deals with nonalloimmune factors that may potentiate alloimmune injury. We discuss infection and reflux/aspiration as examples of allograft injury, which may lead to chronic loss of graft function and BOS. Surgical and nonsurgical treatments aimed at preventing these insults and improving survival are considered. The need for further evidence, including randomized-controlled trials, to evaluate the role of medical and surgical therapies is emphasized by the current literat......
POSTED 05/19/2009 at 11:00 PM --
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Health News of the Day
is a daily summary made from the selected links I post on Twitter. It is in a bullet points format with links to the original sources which include 350 RSS feeds that produce about 2,500 items per day.Effect of Clopidogrel Added to Aspirin in Patients with Atrial Fibrillation: reduced stroke, increased major hemorrhage http://is.gd/ALRaCombination of oral dexamethasone and nebulized epinephrine may significantly reduce hospital admissions in bronchiolitis http://is.gd/zX10In children with scorpion envenomation, scorpion-specific F(ab')2 antivenom IV resolved symptoms within 4 hours http://is.gd/ALPQJAMA Patient Page: Heart Failure http://bit.ly/2gdyWVideo of "Mayo Clinic atrium piano, charming older couple" viewed 1 million times, will be the subject of a case study http://is.gd/wu8NSocia......
POSTED 05/18/2009 at 06:11 AM --
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