Laparoscopic appendicectomy is increasingly used in children. This national retrospective study compared outcomes of pediatric open and laparoscopic appendicectomy. Methods: Length of stay, readmission rates, and mortality in children undergoing open and laparoscopic appendicectomy in English National Health Service Trusts between April 1, 1996, and March 31, 2006, were compared. Procedures coded as emergency excision of appendix (OPCS-4 H01) on the Hospital Episode Statistics (HES) database in patients younger than 15 years were included. Multivariate analysis was used to identify independent predictors of length of hospital stay and mortality. Eighty-nine thousand four hundred ninety-seven appendicectomies were studied, of which 2689 (3%) were performed laparoscopically. The percentage o......
POSTED 06/30/2009 at 06:00 PM --
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NOD2/CARD15 genotype and common gastrointestinal diseases in 43 600 individuals
Conclusions. NOD2/CARD15 polymorphisms are not major risk factors for common gastrointestinal diseases; however, we cannot completely exclude association with appendicitis, anal fissure, fistula and abscess, and gastrointestinal cancer. (Source: Journal of Internal Medicine)...
POSTED 06/29/2009 at 06:00 PM --
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New Appendicitis Test Could Rule Out Surgery
Thousands of Americans suffer from appendicitis every year but the condition can be hard to diagnose. (Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire)...
POSTED 06/29/2009 at 01:21 PM --
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[Appendicitis in the elderly : CRP value as decision support for diagnostic laparoscopy.]
CONCLUSIONS: The CRP value showed a strong correlation with respect to the grade of inflammation and perforation. In conclusion, elderly patients with symptoms of appendicitis and a CRP value higher than 102 mg/l should undergo early diagnostic laparoscopy.
PMID: 19562239 [PubMed - as supplied by publisher] (Source: Der Chirurg)...
POSTED 06/27/2009 at 06:00 PM --
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Methods of Fitting Straight Lines where Both Variables are Subject to Measurement Error.
Authors: Gillard J, Iles T
In this paper errors in variables methods for fitting straight lines to data are reviewed. In these methods the x and y variables are both assumed to be subject to measurement error and not, as in simple least squares linear regression, just one of them. The methods are described in a unified context using the statistical principle of the method of moments. Guidance is given on the choice of an appropriate method of estimating the slope and intercept of the fitted line. Formulas for the approximate standard errors of the estimators are provided in a technical appendix. A numerical example from biochemical studies is included to illustrate the methodology.
PMID: 19500068 [PubMed - as supplied by publisher] (Source: Current Clinical Pharmacology)...
POSTED 06/27/2009 at 10:19 AM --
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[Laparoscopy for suspected appendicitis : Should an appendix that appears normal be removed?]
Authors: Garlipp B, Arlt G
The question whether an appendix found to be macroscopically normal at laparoscopy for suspected appendicitis should be removed remains open to debate. Potential advantages of appendicectomy in all cases include early diagnosis of neoplastic lesions that cannot be detected macroscopically, diagnosis and cure of neurogenic appendicectomy, avoidance of diagnostic confusion in later episodes of abdominal pain, and prevention of appendicitis developing later in life. Therefore, adopting a strategy of always removing the appendix even if it is found to be uninflamed at laparoscopy seems justified as long as it does not imply an increase in postoperative morbidity. We retrospectively studied all patients undergoing laparoscopic appendicectomy in which a "normal app......
POSTED 06/26/2009 at 06:00 PM --
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Mixed-Effects Poisson Regression Models for Meta-Analysis of Follow-Up Studies with Constant or Varying Durations
We present a framework for meta-analysis of follow-up studies with constant or varying duration using the binary nature of the data directly. We use a generalized linear mixed model framework with the Poisson likelihood and the log link function. We fit models with fixed and random study effects using Stata for performing meta-analysis of follow-up studies with constant or varying duration. The methods that we present are capable of estimating all the effect measures that are widely used in such studies such as the Risk Ratio, the Risk Difference (in case of studies with constant duration), as well as the Incidence Rate Ratio and the Incidence Rate Difference (for studies of varying duration). The methodology presented here naturally extends previously published methods for meta-analysis o......
POSTED 06/26/2009 at 01:52 PM --
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Diagnosis of Acute Appendicitis During Pregnancy: A Systematic Review.
Page: 481DOI: 10.1097/OGX.0b013e3181a714bfAuthors: Basaran, Ahmet MD *; Basaran, Mustafa MD + (Source: Obstetrical & Gynecological Survey)...
POSTED 06/26/2009 at 09:39 AM --
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Dipstick test to diagnose appendicitis
A urine test for appendicitis could soon be available that would simplify its diagnosis in children, US researchers have claimed. (Source: HealthcareRepublic GP News)...
POSTED 06/25/2009 at 07:00 PM --
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The Myriad Faces of Imaging Today (and Implications for Tomorrow)
In a previous editorial [], the question “Are we really practicing medicine today?” was posed. That editorial, together with a commentary from James H. Thrall, MD, [], alluded to the advent of new and extraordinary high-tech imaging as it relates to improved, more accurate diagnoses (such as in Dr Thrall's example of the use of computed tomography in the diagnosis of appendicitis), with both authors expressing concern that the inappropriate use of the technology can undermine the essence of the sacred physician-patient relationship, which at its very core involves talking and listening. As a longtime radiologist in a private practice community setting, I would like to further address the challenges posed by the proliferation of the many astounding imaging modalities that have made our ......
POSTED 06/25/2009 at 09:33 AM --
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A new extra-abdominal channel alternative to the mitrofanoff principle: experimental and preliminary clinical experience
CONCLUSION: We were able to confirm feasibility of a new extra-abdominal channel based on the Mitrofanoff principle and successfully reproduced the method in a clinical setting. Follow-up was short and long term results are required before any conclusive judgment can be made. (Source: International Braz J Urol)...
POSTED 06/25/2009 at 03:29 AM --
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Changes in the Epidemiology of Acute Appendicitis and Appendectomy in Danish Children 1996–2004
Eur J Pediatr SurgDOI: 10.1055/s-0029-1224199Abstract Aim of the study was to describe changes in the epidemiology of acute appendicitis in Danish children between 0-19 years of age for the period 1996–2004.[...]© Georg Thieme Verlag KG Stuttgart · New YorkGet connected:Table of contents | Abstract | Full text (Source: European Journal of Pediatric Surgery)...
POSTED 06/25/2009 at 03:25 AM --
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Barium: Appendicitis: case report
(Source: Reactions)...
POSTED 06/25/2009 at 02:34 AM --
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Lever's Histopathology of the Skin
A new edition of the classic has just been released. As with previous editions, this is an authoritative text written and edited by some of the most respected dermatopathologists in the world. The new edition continues the tradition of scholarship and practicality that have made the text one of the best-known names in medical publishing. The images are entirely in color, except for the superb appendix of electron micrographs which remains (appropriately) in splendid black and white. (Source: Journal of the American Academy of Dermatology)...
POSTED 06/25/2009 at 02:32 AM --
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A Urine Test for Appendicitis?
Diagnosing appendicitis, the most common childhood surgical emergency, can be challenging, especially in children. A missed diagnosis can lead to unnecessary surgery in children without appendicitis or to a ruptured appendix and serious complications when the condition is missed. (Source: Medical Headlines From Ivanhoe.com)...
POSTED 06/25/2009 at 12:00 AM --
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Value of intraoperative abdominal cavity culture in appendicectomy: a retrospective study
Appendicectomy is one of the most common surgical emergency procedures. Intraperitoneal culture during appendicectomy is routine practice in some hospitals, while some surgeons advocate abandoning this routine. The aim of our study is to determine the value of intraoperative abdominal cavity culture and its impact on the patient management. Retrospective analysis was performed on 498 patients who underwent appendicectomy over 2.5-year period. The median of the postoperative hospital stay was 2 days, while the median time taken to receive culture results was 3 days. A positive culture was found in 42.6%. Approximately 42.7% of the patients were discharged from the hospital before receiving the culture results. The culture and sensitivity results altered the antibiotic regimen in one patient......
POSTED 06/24/2009 at 06:00 PM --
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Experimental urine test could help diagnose appendicitis in children
A protein found in urine may help indicate which children need surgery for appendicitis, a U.S. study suggests. (Source: CBC | Health)...
POSTED 06/24/2009 at 02:53 PM --
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Urine Protein Testing May Help Detect Appendicitis
Urine testing for leucine-rich alpha-2-glycoprotein and other biomarkers may improve the ability of doctors to diagnose acute appendicitis. Reuters Health Information (Source: Medscape Emergency Medicine Headlines)...
POSTED 06/24/2009 at 11:25 AM --
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A Urine Test for Appendicitis
A newly discovered protein may be the key to a diagnostic test that could help emergency room doctors identify cases of appendicitis quickly and cheaply (Source: TIME.com: Top Science and Health Stories)...
POSTED 06/24/2009 at 09:05 AM --
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Laparoscopy: a safe approach to appendicitis during pregnancy
Conclusions This article is the largest hospital-based series evaluating the laparoscopic versus open approach for pregnant patients with
presumed acute appendicitis. While methodological limitations preclude a definitive recommendation, laparoscopy appears to
be a safe, feasible, and efficacious approach for pregnant patients with presumed acute appendicitis. We conclude that it
is likely not the surgical approach but the underlying diagnosis combined with maternal factors that determine the risk for
pregnancy complications. A benefit of laparoscopy is the diagnostic ability to identify other intra-abdominal pathology which
may mimic appendicitis and harbor pregnancy risks.
Content Type Journal ArticleDOI 10.1007/s00464-009-0571-7Authors
Eran Sadot, The Mount Sina......
POSTED 06/24/2009 at 01:08 AM --
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