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Anemia Medical and Health News Headlines
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All Recent Anemia Medical Condition News Headlines |
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Boy, 4, with one in 6bn condition needs pint of blood every fortnight to survive
Jamie Andrews, four, has a one of a kind chromosome disorder called Diamond Blackfan Anaemia. (Source: the Mail online | Health)...
POSTED 03/10/2010 at 07:42 PM --
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First-time buyers boost home sales
First-time homebuyers in California have given a boost to the anemic residential real estate market. (Source: bizjournals.com Health Care:Health Insurance headlines)...
POSTED 03/10/2010 at 01:32 PM --
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Inhalant Abuse and Hemoptysis: Is there really cause and effect?
2 out of 5 stars
Inhalant Abuse: A Case of Hemoptysis Associated with Halogenated Hydrocarbon Abuse. Schloneger M et al. Pediatr Emerg Care 2009;25:754-757.
Abstract
This case report describes an 18-year-old male with respiratory difficulty — initially treated as pneumonia — that eventually was diagnosed as massive pulmonary hemorrhage. Many rare causes of this condition — Goodpasture syndrome, bacterial and viral pneumonia, Wegener granulomatosis, etc — were ruled-out. Despite intensive treatment, the patient’s respiratory condition continued to deteriorate and he died on the 11th hospital day.
Because the patient’s mother revealed that he had been huffing keyboard cleaner (tetrafluoroethane), the authors report this association but are careful ......
POSTED 03/09/2010 at 07:19 PM --
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Influence of carotene-rich vegetable meals on the prevalence of anaemia and iron deficiency in Filipino schoolchildren
Authors: C C Maramag, J D Ribaya-Mercado, P Rayco-Solon, J A A Solon, L W Tengco, J B Blumberg
& F S Solon (Source: European Journal of Clinical Nutrition)...
POSTED 03/09/2010 at 06:00 PM --
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Relationship between anaemia and cognitive functions in elderly people.
CONCLUSION: In the elderly anaemic group, the dependency for daily activities that require physical effort was higher compared to the nonanaemic group. The MMSE score in the elderly anaemic group was lower than subjects who had normal haemoglobin levels. We conclude that anaemia may impair cognitive functions and some daily living activities in the elderly.
PMID: 20206877 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)...
POSTED 03/09/2010 at 09:36 AM --
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Anemia in diabetic patients at an internal medicine ward: Clinical correlates and prognostic significance.
CONCLUSION: Frequency of anemia was increased in diabetic patients admitted to the Internal Medicine Departments, compared to the studies performed on ambulatory patient populations. Anemia was multifactorial and associated with higher mortality, predominantly from infections. Males with albuminuria and heart failure were at higher risk of death.
PMID: 20206878 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)...
POSTED 03/09/2010 at 09:36 AM --
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Functional vitamin B12 deficiency in alcoholics: An intriguing finding in a retrospective study of megaloblastic anemic patients.
CONCLUSION: Some alcohol-dependent patients with megaloblastic anemia may respond to vitamin B12 treatment despite normal cobalamin serum levels; therefore in alcoholics caution is urged in the interpretation of these vitamin assays, because of possible functional vitamin B12 deficiency.
PMID: 20206879 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)...
POSTED 03/09/2010 at 09:36 AM --
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Baseline characteristics and outcome in Romanian patients with Gaucher disease type 1.
CONCLUSIONS: The genotype N370S/L444P is frequent in our patients, in line with the severe phenotypes. ERT improved haematological parameters and visceromegaly, without a clear benefit for bone mineral density. To attain therapeutic goals, an early treatment start with optimal dosage is mandatory.
PMID: 20206881 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)...
POSTED 03/09/2010 at 09:36 AM --
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Phase II Trial of Weekly Bortezomib in Combination With Rituximab in Relapsed or Relapsed and Refractory Waldenstrom Macroglobulinemia [Hematologic Malignancies]
Conclusion
The combination of weekly bortezomib and rituximab showed significant activity and minimal neurologic toxicity in patients with relapsed WM. (Source: Journal of Clinical Oncology)...
POSTED 03/08/2010 at 05:01 PM --
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History and Current Status of Newborn Screening for Hemoglobinopathies
The impact of hemoglobinopathies on healthcare in the United States, particularly sickle cell disease (SCD), has been significant. Enactment of the Sickle Cell Anemia Control Act in 1972 significantly increased the federal interest in the SCDs and other hemoglobinopathies. Only since May 1, 2006, have all states required and provided universal newborn screening for SCD despite a national recommendation to this effect in 1987. In this article, we review the history of screening for SCD and other hemoglobinopathies, along with federal and state activities that have contributed to improved health outcomes for patients with SCD, as well as current newborn screening practices. We also chronicle the federal activities that have helped to shape and to refine laboratory screening and diagnostic pr......
POSTED 03/08/2010 at 11:41 AM --
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Lipid levels in sickle-cell disease associated with haemolytic severity, vascular dysfunction and pulmonary hypertension
Pulmonary hypertension (PH) in sickle cell disease (SCD) is an emerging and important clinical problem. In a single-institution adult cohort of 365 patients, we investigated lipid and lipoprotein levels and their relationship to markers of intravascular haemolysis, vascular dysfunction and PH. In agreement with prior studies, we confirm significantly decreased plasma levels of total cholesterol, high-density lipoprotein-cholesterol (HDL-C) and low-density lipoprotein-cholesterol (LDL-C) in SCD versus ethnically-matched healthy controls. Several cholesterol parameters correlated significantly with markers of anaemia, but not endothelial activation or PH. More importantly, serum triglyceride levels were significantly elevated in SCD compared to controls. Elevated triglyceride levels correlat......
POSTED 03/07/2010 at 06:00 PM --
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Effect of eculizumab on haemolysis-associated nitric oxide depletion, dyspnoea, and measures of pulmonary hypertension in patients with paroxysmal nocturnal haemoglobinuria
Pulmonary hypertension (PH) is a common complication of haemolytic anaemia. Intravascular haemolysis leads to nitric oxide (NO) depletion, endothelial and smooth muscle dysregulation, and vasculopathy, characterized by progressive hypertension. PH has been reported in patients with paroxysmal nocturnal haemoglobinuria (PNH), a life-threatening haemolytic disease. We explored the relationship between haemolysis, systemic NO, arginine catabolism and measures of PH in 73 PNH patients enrolled in the placebo-controlled TRIUMPH (Transfusion Reduction Efficacy and Safety Clinical Investigation Using Eculizumab in Paroxysmal Nocturnal Haemoglobinuria) study. At baseline, intravascular haemolysis was associated with elevated NO consumption (P < 0·0001) and arginase-1 release (P < 0·0001). Almost......
POSTED 03/07/2010 at 06:00 PM --
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Weekly paclitaxel plus carboplatin is an effective nonanthracycline-containing regimen as neoadjuvant chemotherapy for breast cancer.
CONCLUSIONS: Weekly PCb regimen was very active and tolerable as neoadjuvant treatment of breast cancer. This weekly PCb regimen should consider as a reasonable nonanthracycline-containing option in the neoadjuvant treatment of breast cancer.
PMID: 20211870 [PubMed - as supplied by publisher] (Source: Ann Oncol)...
POSTED 03/07/2010 at 06:00 PM --
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A multiprotein complex involved in the DNA damage response network of Fanconi anemia, breast cancer, and Bloom syndrome
The DNA Repair Interest Group is concerned with all forms of DNA damage and repair. As a major defense against environmental damage to cells DNA repair is present in all organisms examined including bacteria, yeast, drosophila, fish, amphibians, rodents and humans. The members of the DNA Repair Interest Group perform research in areas including DNA repair enzymology and fine structure, mutagenesis, gene and cell cycle regulation, protein structure, and human disease.
For more information, visit the
DNA Repair Interest GroupAir date: 3/16/2010 12:30:00 PM (Source: Videocast - All Events)...
POSTED 03/05/2010 at 08:30 AM --
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Vulnerability to anemia may underlie beta-blocker peri-operative risk
The putative excess risk for certain peri-operative complications in patients given beta blockers may be caused by the drugs increasing patients’ vulnerability to the effects of anemia, research suggests. (Source: MedWire News - Anesthesiology)...
POSTED 03/04/2010 at 06:00 PM --
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[Case Report] Altered pain perception in schizophrenia
In June, 2009, a 51-year-old woman presented with a 4-day history of abdominal swelling and fever, and a 2-week history of loss of appetite. There was no history of abdominal pain or nausea. She was febrile (38·4°C) and her abdomen was swollen but soft without spontaneous pain or tenderness. She had a history of schizophrenia since the age of 40 years which was well controlled with perospirone 12 mg/day and quetiapine 150 mg/day. At the age of 45 years, she was diagnosed with diabetes mellitus and had achieved good glycaemic control (HbA1c 6·5%) with biphasic insulin aspart 30 (6 U/day). There was no sign of obvious peripheral neuropathy. Laboratory test results showed normocytic anaemia (haemoglobin 95 g/L), leucocytosis (13·3×109/L) with neutrophilia (91·5%), high concentration of ......
POSTED 03/04/2010 at 06:00 PM --
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Fixed-dose-rate gemcitabine: a viable first-line treatment option for advanced pancreatic and biliary tract cancer.
Conclusions. Currently available evidence, including this updated analysis, supports the use of FDR-Gem as a first-line option in advanced PDAC, and possibly in BTC, patients and prompts the continued evaluation of this approach in combination regimens.
PMID: 20189980 [PubMed - in process] (Source: The Oncologist)...
POSTED 03/04/2010 at 05:04 PM --
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International Women’s Day: A girl called 'Good News'
In Burundi becoming pregnant is a matter of life and death. According to the World Health Organisation, the maternal mortality rate is 11 for every 1,000 live births, while the neonatal mortality rate is 41 per 1,000 live births.
Since 2008, Médecins Sans Frontières (MSF) has been running a centre for obstetric emergencies in the town of Kabezi, south of the capital Bujumbura. The centre provides free specialised medical care during pregnancy and delivery, and treats an average of 250 women a month.
Mary Nicizanye, 30, is one of those women. She is sitting in the ward at the MSF centre. It has been four days since she gave birth to a little girl. Beads of sweat run down her neck, but her eyes are bright.
Before she gave birth, Mary was brought to a local health centre suffering f......
POSTED 03/04/2010 at 02:12 PM --
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Red blood cells transfusion in intensive care unit
CONCLUSIONS: Politrauma and sepsis/sepsis chock were the pre diagnosis criteria. A low hemoglobin level is the main clinical criteria with average hemoglobin pre - transfusion was 8,11 g/dL. (Source: Revista Brasileira de Terapia Intensiva)...
POSTED 03/04/2010 at 11:26 AM --
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Analysis of novel sph (spherocytosis) alleles in mice reveals allele-specific loss of band 3 and adducin in {alpha}-spectrin-deficient red cells
Five spontaneous, allelic mutations in the -spectrin gene, Spna1, have been identified in mice (spherocytosis [sph], sph1J, sph2J, sph2BC, sphDem). All cause severe hemolytic anemia. Here, analysis of 3 new alleles reveals previously unknown consequences of red blood cell (RBC) spectrin deficiency. In sph3J, a missense mutation (H2012Y) in repeat 19 introduces a cryptic splice site resulting in premature termination of translation. In sphIhj, a premature stop codon occurs (Q1853Stop) in repeat 18. Both mutations result in markedly reduced RBC membrane spectrin content, decreased band 3, and absent β-adducin. Reevaluation of available, previously described sph alleles reveals band 3 and adducin deficiency as well. In sph4J, a missense mutation occurs in the C-terminal EF hand domain (C......
POSTED 03/04/2010 at 11:00 AM --
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