Basal serum tryptase as risk assessment for severe Hymenoptera sting reactions in elderly
Conclusions: Our data confirm serum tryptase as a risk factor for severe anaphylactic reaction to hymenoptera stings. Furthermore, we give first evidence that basal serum tryptase levels increase continuously with age and being an indicator for either increased mast cell load or reactivity this can at least partly be responsible for the observed aggravated allergic reactions in elderly people. As those patients are at increased risk for life-threatening anaphylactic reactions, it should be considered to adjust VIT especially in elderly patients with elevated tryptase levels as recommended for patients with mastocytosis by increasing venom doses during VIT and by considering its life-long continuation. (Source: Allergy)...
POSTED 01/31/2010 at 06:00 PM --
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Food-dependent anaphylaxis with serum IgE immunoreactive to dairy products containing high-molecular-weight proteins
Food-induced anaphylaxis is one of the most common causes of anaphylaxis . Establishing the cause of recurrent anaphylaxis is one of the most important goals of management because identification of the responsible allergens allows avoidance of further exposure. (Source: Journal of Dermatological Science)...
POSTED 01/28/2010 at 08:12 AM --
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Budesonide/formoterol: Anaphylaxis: case report
(Source: Reactions)...
POSTED 01/27/2010 at 08:05 AM --
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Carboplatin: Anaphylaxis in an infant: case report
(Source: Reactions)...
POSTED 01/27/2010 at 08:05 AM --
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Eculizumab: Possible anaphylaxis (first report) in an elderly patient: case report
(Source: Reactions)...
POSTED 01/27/2010 at 08:05 AM --
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Lidocaine: Anaphylaxis: case report
(Source: Reactions)...
POSTED 01/27/2010 at 08:05 AM --
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Piperacillin: Anaphylaxis: case report
(Source: Reactions)...
POSTED 01/27/2010 at 08:05 AM --
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Severe anaphylaxis to the antiseptic polyhexanide
(Source: Allergy)...
POSTED 01/22/2010 at 06:00 PM --
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Varicella vaccines: Anaphylaxis in a child due to gelatin excipient: case report
(Source: Reactions)...
POSTED 01/19/2010 at 08:09 AM --
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Systemic anaphylaxis caused by moxifloxacin.
Authors: Sánchez-Morillas L, Rojas Pérez-Ezquerra P, Reaño-Martos M, Laguna-Martínez JJ, Gómez-Tembleque P
PMID: 20089346 [PubMed - as supplied by publisher] (Source: Allergologia et Immunopathologia)...
POSTED 01/17/2010 at 06:00 PM --
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Induction of Tolerance to Warfarin after Anaphylaxis with a Desensitization Protocol
Cardiology 2010;115:174175 (DOI:10.1159/000275922) (Source: Karger Publishers)...
POSTED 01/15/2010 at 05:00 PM --
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Tyrosine phosphatase SHP-1 in allergic and anaphylactic inflammation
Abstract Protein tyrosine phosphatase SHP-1 is an essential regulatory molecule in many different signaling pathways. The biological
importance of SHP-1 is underscored by the motheaten mutant mouse strains with immunological disorders involving multiple organs
and by the close association of aberrant SHP-1 expression with several human diseases. Recent studies provided some compelling
evidence that supports a role of SHP-1 in regulating mast cell development and function and also in regulating type 2 allergic
inflammatory responses in both innate and adaptive immune responses. In this article, we summarize the recent advancement
of our understanding of this interesting phosphatase in the important area of allergic inflammation.
Content Type Journal ArticleDOI 10.1007/s12......
POSTED 01/14/2010 at 06:47 PM --
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Multiple T cell epitope peptides suppress allergic responses in an egg allergy mouse model by the elicitation of forkhead box transcription factor 3- and transforming growth factor-β-associated mechanisms
In this study, we built on the information obtained from the recent identification of three immunodominant T cell epitopes of hen ovalbumin (OVA), a major egg allergen, to assess the therapeutic potential of PIT for food allergy, using the BALB/c mouse model. Groups of mice were sensitized to OVA by repeated oral gavages, and subsequently administered with single or multiple synthetic peptides containing OVA T cell epitopes. Following the peptide administration period, all mice were orally challenged with high doses of OVA to elicit active anaphylaxis. Serum, spleen, and intestinal tissues were collected for the determination of immunoglobulin levels, cytokine secretions, and intestinal gene expression. Significantly lower anaphylactic scores were exhibited by mice that received multiple e......
POSTED 01/13/2010 at 06:00 PM --
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[Anaphylactic shock due to patent blue: Four case report and review of literature.]
CONCLUSION: We find an incidence of 1.06% of allergy but only 0.25% of anaphylactic shock (grade III). These rare but serious cases must weigh up the benefits and risks of using blue dye. We suggest using blue dye injection only in case of radioisotope detection failure. Of course, this approach must be evaluated.
PMID: 20079974 [PubMed - as supplied by publisher] (Source: Journal de Gynecologie, Obstetrique et Biologie de la Reproduction)...
POSTED 01/13/2010 at 06:00 PM --
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Cefotiam: Anaphylaxis followed by stress-induced cardiomyopathy (first report): case report
(Source: Reactions)...
POSTED 01/11/2010 at 08:23 AM --
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Epinastine: Anaphylaxis associated with benzalkonium chloride excipient: case report
(Source: Reactions)...
POSTED 01/11/2010 at 08:23 AM --
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Infliximab: Anaphylaxis and bilateral parotidomegaly: case report
(Source: Reactions)...
POSTED 01/11/2010 at 08:23 AM --
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Measles mumps and rubella virus vaccine/varicella vaccine: Anaphylaxis in a child due to gelatin excipient: case report
(Source: Reactions)...
POSTED 01/11/2010 at 08:23 AM --
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Propofol: Anaphylaxis: case report
(Source: Reactions)...
POSTED 01/11/2010 at 08:23 AM --
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Sciele Introduces Adrenaclick™ (epinephrine Injection, USP) Auto-Injector For The Emergency Treatment Of Anaphylaxis
Sciele Pharma, Inc., a Shionogi company, today announced the U.S. availability of Adrenaclick™, a single-dose, epinephrine auto-injector for the emergency treatment for severe allergic reactions (Type I) such as anaphylaxis. Adrenaclick™ will be available as a single unit or a convenient Two-Pack. It is also available in two dosing options (0.15 mg and 0.3 mg). Adrenaclick™ delivers epinephrine, the drug of choice for anaphylactic reactions, with the use of an auto-injector... (Source: Health News from Medical News Today)...
POSTED 01/11/2010 at 05:00 AM --
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