The effect of isotretinoin treatment on plasma homocysteine levels in acne vulgaris
Isotretinoin has revolutionized the treatment of acne by improving the cosmetic outcome and decreasing the psychological damage. However, use of isotretinoin is associated with significant side-effects such as mucocutaneous involvement, dyslipidaemia and liver dysfunction, as indicated by increases in liver enzymes. The responsible enzyme for homocysteine metabolism, cystathionine-[beta]-synthase, might also be affected by isotretinoin-induced liver dysfunction, which leads to hyperhomocysteinaemia, an independent risk factor for thrombovascular diseases. The aim of this study was to evaluate homocysteine levels and the responsible vitamins for its metabolism in patients with moderate to severe acne vulgaris on isotretinoin treatment, before and after treatment. We found increased level of......
POSTED 03/07/2010 at 06:00 PM --
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New Treatments and Good Skin Care Helping Patients Control Acne and Rosacea
Source: American Academy of Dermatology
Related MedlinePlus Pages: Acne, Rosacea (Source: MedlinePlus Health News)...
POSTED 03/06/2010 at 09:58 AM --
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Severe Acne Responds to Combo Therapy (CME/CE)
Patients with severe acne had significantly greater improvement when topical adapalene/benzoyl peroxide (Epiduo) was added to oral doxycycline, according to results of a randomized clinical trial. (Source: MedPage Today Dermatology)...
POSTED 03/06/2010 at 06:43 AM --
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New Treatments and Good Skin Care Helping Patients Control Acne and Rosacea
Acne and rosacea are two seemingly different skin conditions that have one important thing in common: both are chronic and extremely common skin conditions. However, dermatologists recommend that with proper diagnosis, treatment and a healthy dose of good, old-fashioned skin care, acne and rosacea can be less of a nuisance for patients. (Source: ScienceDaily Headlines)...
POSTED 03/05/2010 at 11:00 PM --
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Severe Acne Responds to Combo Therapy (CME)
Patients with severe acne had significantly greater improvement when topical adapalene/benzoyl
peroxide (Epiduo) was added to oral doxycycline, according to results of a randomized clinical trial. (Source: Modern Medicine)...
POSTED 03/04/2010 at 06:00 PM --
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Annual Evidence Update on acne vulgaris: 1-5 March 2010
Source: NHS Evidence
Area: News
NHS Evidence - Skin Disorders has produced its fourth annual evidence update on acne vulgaris, including new guidance and systematic reviews published in the last year. A 'What's new?' section provides an expert commentary on the new evidence and its implications for clinical practice. Please see the link below for details. (Source: NeLM - News)...
POSTED 02/28/2010 at 06:00 PM --
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Annual Evidence Update on Acne Vulgaris: 1-5 March 2010
An update of the evidence on this topic from NHS Evidence - skin disorders (Source: NLH)...
POSTED 02/28/2010 at 07:55 AM --
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Individualizing Treatment for Adolescent Acne to Achieve Optimal Outcomes
Jo Ann Serota, MSN, RN, CPNP (Source: Journal of Pediatric Health Care)...
POSTED 02/26/2010 at 09:16 AM --
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Use of Oral Budesonide in the Management of Protein-Losing Enteropathy After the Fontan Operation [ORIGINAL ARTICLES: PEDIATRIC CARDIAC]
Conclusions
Oral budesonide is an effective therapy for treating protein-losing enteropathy after the Fontan operation. To maintain response, low-dose therapy must be continued. (Source: The Annals of Thoracic Surgery)...
POSTED 02/23/2010 at 04:46 PM --
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Use of Oral Budesonide in the Management of Protein-Losing Enteropathy After the Fontan Operation.
CONCLUSIONS: Oral budesonide is an effective therapy for treating protein-losing enteropathy after the Fontan operation. To maintain response, low-dose therapy must be continued.
PMID: 20172140 [PubMed - as supplied by publisher] (Source: The Annals of Thoracic Surgery)...
POSTED 02/23/2010 at 07:10 AM --
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Galderma Announces Positive Results Of Study Evaluating A Regimen Of Epiduo Gel And Doxycycline 100mg For Patients With Significant Acne
–Results Could Help Redefine Acne Treatment Regimens and
Validate Established Consensus Guidelines–
Fort Worth, TX – February X, 2009 – Results from the
ACCESS study found that the addition of Epiduo® (adapalene... (Source: Drugs.com - Clinical Trials)...
POSTED 02/22/2010 at 12:57 PM --
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Retin-A Researcher Albert Kligman Dies
From Associated Press (February 21, 2010)
PHILADELPHIA -- Dermatologist Albert M. Kligman, whose research
led to discoveries including the acne and wrinkle drug Retin-A but
whose pioneering work was overshadowed by his experiments... (Source: Drugs.com - Pharma News)...
POSTED 02/22/2010 at 06:37 AM --
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Photodynamic therapy for acne vulgaris: a randomized, controlled, split-face clinical trial of topical aminolevulinic acid and pulsed dye laser therapy
Conclusions PDT with the treatment regimen employed here may be beneficial for a subgroup of patients with inflammatory acne. (Source: Journal of Cosmetic Dermatology)...
POSTED 02/21/2010 at 06:00 PM --
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Acne vulgaris and depression: a retrospective examination
Conclusions Acne is a disease that affects people of all ages both physically and psychologically. A correlation exists between clinical depression and acne patients, particularly those older than 36. "There is no single disease which causes more psychic trauma and more maladjustment between parents and children, more general insecurity and feelings of inferiority and greater sums of psychic assessment than does acne vulgaris" (Sulzberger, 19481). (Source: Journal of Cosmetic Dermatology)...
POSTED 02/21/2010 at 06:00 PM --
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Dermatologist Albert Kligman dies, research led to wrinkle drug Retin-A
PHILADELPHIA (AP) — Dermatologist Albert M. Kligman, whose research led to discoveries including the acne and wrinkle drug Retin-A but whose pioneering work was overshadowed by his experiments involving prisoners, has died. He was 93.
Kligman... (Source: OrlandoSentinel: Medical Research)...
POSTED 02/21/2010 at 04:55 AM --
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Faith makes regulating herbal medicine difficult
A judge this week called for traditional medicine to be regulated, but it's not easy when practitioners make claims based on faithYou may have read about Ying Wu this week: a traditional Chinese medicine doctor operating out of a shop in Chelmsford, Essex, who for several years prescribed pills with high doses of a dangerous substance to treat the acne of senior civil servant Patricia Booth, 58. Following this, her patient lost both kidneys, developed urinary tract cancer, had a heart attack, and is on dialysis three times a week. Judge Jeremy Roberts gave Ying a two-year conditional discharge, saying she could not be blamed, because she did not know the pills were harmful and the practice of traditional Chinese medicine is unregulated in Britain, a situation that he suggests should be rem......
POSTED 02/19/2010 at 06:00 PM --
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Consensus Recommendations on the Use of an Erbium-Doped 1,550-nm Fractionated Laser and Its Applications in Dermatologic Laser Surgery
Nonablative fractional photothermolysis has revolutionized the way we treat a number of common skin conditions with laser technology. A comprehensive guide is needed for clinicians using this technology to treat specific skin conditions in various skin types. Recommendations were made from a recent round table discussion among experienced physicians and a review of recent literature findings. Optimal laser parameters are dependent on patient skin type and condition. We recommended guidelines for the successful treatment of several common skin conditions on and off the face using nonablative fractional photothermolysis. Specific conditions were dyschromia, rhytides, acne scars, surgical scars, melasma, and striae distensae. We developed reproducible guidelines to most effectively treat a va......
POSTED 02/18/2010 at 06:00 PM --
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New Jersey Jury Awards $25.16 Million To Patient Whose Use Of Roche Acne Medication Accutane Found To Cause Severe Bowel Illness
In another major courtroom verdict linking powerful acne medication Accutane with long-term inflammatory bowel disease (IBD), a nine-person New Jersey jury has found that pharmaceutical maker Hoffman-La Roche Inc. failed to provide an adequate warning of the possible condition to Andrew McCarrell's prescribing physician, which then led to his development of chronic IBD. (Source: Pharmaceutical Online News)...
POSTED 02/17/2010 at 02:42 AM --
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Dermabrasion for Acne Scars During Treatment with Oral Isotretinoin
Oral isotretinoin is the criterion standard treatment for severe inflammatory acne associated with scar development. Atypical or exaggerated cicatrization related to oral isotretinoin was reported throughout the 1980s and 1990s. Dermabrasion for atrophic acne scar revision is not recommended 6 to 12 months from the end of oral isotretinoin treatment. To evaluate wound healing after localized dermabrasion in patients receiving oral isotretinoin. Interventional, prospective study involving seven patients taking oral isotretinoin to treat acne and with atrophic acne scars on the face. Manual dermabrasion was performed on all patients in an area of approximately 1 cm2, and a 6-month reepithelization follow-up by clinical evaluation was conducted. All patients presented normal cicatrization evo......
POSTED 02/16/2010 at 06:00 PM --
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Accutane linked to severe skin reactions
Rare but potentially deadly skin reactions have been found in people using Accutane to treat severe acne, Health Canada says. (Source: CBC | Health)...
POSTED 02/16/2010 at 01:26 PM --
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