Novel in vitro assays for the characterization of EMT in tumourigenesis.
Conclusion: The Spindle Index and the novel chemoattractant assay are valuable adjunctive assays for objective characterization of EMT changes during tumourigenesis.
PMID: 20208135 [PubMed - in process] (Source: Cellular Oncology)...
POSTED 03/10/2010 at 07:06 AM --
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GU Cancers Symposium 2010: ASCO ASTRO SUO - Cancers of the urothelium - Session Highlights
SAN FRANCISCO, CA, USA (UroToday.com) - In this session focused on bladder cancer, four presentations provided updates on detection and... (Source: UroToday)...
POSTED 03/09/2010 at 05:04 PM --
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GU Cancers Symposium 2010: ASCO ASTRO SUO - 15-year outcomes of selective bladder preservation ...
SAN FRANCISCO, CA, USA (UroToday.com) - This presentation provided a review of data from Massachusetts General Hospital on the long-term... (Source: UroToday)...
POSTED 03/09/2010 at 05:04 PM --
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Is single-dose postoperative intravesical gemcitabine effective to prevent recurrence in patients with non-muscle invasive bladder cancer?
Jain Abhishek, Goel Apul, Sankhwar S NIndian Journal of Urology 2010 26(1):153-155 (Source: Indian Journal of Urology)...
POSTED 03/09/2010 at 10:12 AM --
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Functional significance of the hepaCAM gene in bladder cancer
Background:
The hepaCAM gene encodes a new immunoglobulin-like cell adhesion molecule, and its expression is suppressed in a variety of human cancers. Additionally, hepaCAM possesses properties often observed in tumor suppressor genes. However, the expression and biological function of hepaCAM has not been investigated in bladder cancer. We therefore sought to examine hepaCAM expression and the relationship between its structure and function in human transitional cell carcinoma of bladder (TCCB).
Methods:
hepaCAM expression was evaluated in 28 normal and 34 TCCB bladder specimens and 2 TCCB cell lines using semi-quantitative RT-PCR. The wild-type hepaCAM and the extracellular domain-truncated mutant gene were transfected into the TCCB cell line T24, and the biological properties of both th......
POSTED 03/07/2010 at 06:00 PM --
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Reiter's syndrome following intravesical instillation of bacillus Calmette-Guerin - Abstract
The Department of Urology, Chichibu City Hospital. (Source: UroToday)...
POSTED 03/07/2010 at 05:00 PM --
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In-depth investigation of the molecular pathogenesis of bladder cancer in a unique 26-year old ...
The molecular characteristics and the clinical disease course of bladder cancer (BC) in young patients remain largely unresolved. (Source: UroToday)...
POSTED 03/07/2010 at 05:00 PM --
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Predictive Biosciences To Present Novel Combination Approach To Molecular Cancer Diagnostics At 2010 Genitourinary Cancers Symposium
Predictive Biosciences announced that the Company will be presenting its novel Multi-Analyte Diagnostic Readout (MADR™) approach to the development of a non-invasive, urinary biomarker based assay for the detection of bladder cancer during the 2010 Genitourinary Cancers Symposium (GU Symposium), being held March 5-7 in San Francisco. The GU Symposium is co-sponsored by the American Society of Clinical Oncology (ASCO), the American Society for Radiation Oncology (ASTRO) and the Society of Urologic Oncology (SUO)... (Source: Health News from Medical News Today)...
POSTED 03/07/2010 at 02:00 AM --
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Health headlines: Binge drinking, Wii workout games and CPR
Other stories we’ve been reading:
Read one father’s story on how he became an advocate for safer teen driving. Check out these safe driving tips for your teen. [Read about the dangers of drowsy driving.]
Advertising guilt doesn’t curb binge drinking. Teen alcohol and marijuana use is on the rise. [A recent teen drug survey predicted this.] Young people who smoke marijuana for long periods of time are more likely to risk psychosis.
Despite studies proving otherwise, some parents still believe that vaccines cause autism. Gene therapy is closer to restoring eyesight to blind patients. [Read about how a novel surgery saves one baby’s vision.] A blood test can help sort out milk allergies. [Watch Brett go through a milk exposure desensitization trial.]
Screening athletes could prevent s......
POSTED 03/06/2010 at 07:00 AM --
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Cytoscopy Alone Is Most Cost-Effective in Monitoring Bladder Cancer
Various urine tests are increasingly added to cytoscopy in the monitoring of bladder cancer. Which approach is most cost-effective? Medscape Medical News (Source: Medscape Today Headlines)...
POSTED 03/05/2010 at 03:11 PM --
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ASCO GU: Urine Screening Not Worth the Money in Bladder CA
SAN FRANCISCO (MedPage Today) -- Adding urine tests to standard cytoscopy for surveillance after non-muscle invasive bladder cancer may increase cost without boosting detection, according to a prospective cost-effectiveness study. (Source: MedPage Today Hematology/Oncology)...
POSTED 03/05/2010 at 07:13 AM --
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Cystoscopy alone most cost-effective method to detect bladder cancer
recurrence
(Source: HemOncToday.com)...
POSTED 03/05/2010 at 03:59 AM --
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Costly Tests May Not Help Detect Bladder Cancer Recurrence
In a new study from The University of Texas M. D. Anderson Cancer Center, researchers found that cystoscopy, the standard for screening for recurrence of early-stage bladder cancer, is a cost-effective method of detecting tumors... (Source: Cancer / Oncology News From Medical News Today)...
POSTED 03/05/2010 at 02:00 AM --
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Cystoscopy suffices for bladder cancer
HOUSTON, March 4 (UPI) -- U.S. researchers suggest cystoscopy alone suffices as a test for recurrent bladder cancer. (Source: Health News - UPI.com)...
POSTED 03/04/2010 at 10:54 PM --
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Subepithelial growth patterns in urothelial carcinoma-frequency and prognostic significance.
CONCLUSIONS: Subepithelial growth is not an uncommon in bladder cancer. It is more frequent in high-grade and high-stage tumors. The findings of this study suggest that subepithelial growth carries a higher risk for stage progression (EGP and VBNI) and mortality (EGP), but not tumor recurrence.
PMID: 20207557 [PubMed - as supplied by publisher] (Source: Urologic Oncology)...
POSTED 03/04/2010 at 06:00 PM --
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Bladder tumor risk higher after childhood cancer
NEW YORK (Reuters Health) - Childhood cancer survivors are at a four-fold increased risk of developing new cancers of the bladder later in life, new research shows. (Source: Reuters: Health)...
POSTED 03/04/2010 at 03:13 PM --
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Studies Presented At 2010 Genitourinary Cancers Symposium Advance Management, Treatment Of Prostate And Bladder Cancers
New studies on the treatment of genitourinary cancers were released today in advance of the third annual Genitourinary Cancers Symposium, being held March 5-7, 2010, at the San Francisco Marriott... (Source: Cancer / Oncology News From Medical News Today)...
POSTED 03/04/2010 at 10:00 AM --
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Decursin inhibits growth of human bladder and colon cancer cells via apoptosis, G1-phase cell cycle arrest and extracellular signal-regulated kinase activation.
Authors: Kim WJ, Lee SJ, Choi YD, Moon SK
Decursin, a pyranocoumarin isolated from the Korean Angelica gigas root, has demonstrated anti-cancer properties. In the present study, we found that decursin inhibited cell viability in cultured human urinary bladder cancer 235J cells and colon cancer HCT116 cells. The inhibited proliferation was due to apoptotic induction, because both cells treated with decursin dose-dependently showed a sub-G1 phase accumulation and an increased cytoplasmic DNA-histone complex. Cell death caused by decursin was also associated with the down-regulation of anti-apoptotic factor Bcl-2 and the up-regulation of pro-apoptotic molecules cytochrome c, caspase 3 and Bax. Treatment of both types of cancer cells with decursin resulted in G1-phase cell cycle arrest, as......
POSTED 03/04/2010 at 07:22 AM --
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ASCO: Cystoscopy Alone More Cost-Effective in Surveillance
Follow up screening for non-muscle-invasive bladder cancer recurrence with only cystoscopy is more
cost-effective than combined cystoscopy with urinary biomarker detection, and is associated with a lower incidence
of false-positive results, according to research presented at the 2010 Genitourinary Cancers Symposium, held from
March 5 to 7 in San Francisco. (Source: Modern Medicine)...
POSTED 03/03/2010 at 06:00 PM --
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Robot-assisted radical cystectomy: An expert panel review of the current status and future direction.
CONCLUSIONS: Initial reports of RARC demonstrate feasibility of technique, early oncologic outcomes, and learning curve experiences. Surgeons learning RARC should select patients without clinical evidence of locally advanced disease, and consider a second look open node dissection. Experienced surgeons have demonstrated the possibility of reduced blood loss, opiate requirement, and hospital stay. Moving forward, an international consortium has been organized to address the unmet needs of prospective comparisons with long-term oncologic outcomes, standardized complication reporting, and quality of life.
PMID: 20207174 [PubMed - as supplied by publisher] (Source: Urologic Oncology)...
POSTED 03/03/2010 at 06:00 PM --
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